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Biocomputational prediction of small non-coding RNAs in Streptomyces
BackgroundThe first systematic study of small non-coding RNAs (sRNA, ncRNA) in Streptomyces is presented. Except for a few exceptions, the Streptomyces sRNAs, as well as the sRNAs in other genera ofExpand
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CobB1 deacetylase activity in Streptomyces coelicolor.
Silent information regulators are NAD(+)-dependent enzymes that display differential specificity toward acetylated substrates. This report provides first evidence for deacetylation activity of CobB1Expand
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The biosynthesis of tetracycline
It was initially assumed that the tetracycline nucleus originated by the polyketide pathway from acetylor malonyl-CoA. Evaluation of the results of experiments with labelled precursors and on theExpand
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Sequencing of the tuf1 gene and the phosphorylation pattern of EF-Tu1 during development and differentiation in Streptomyces collinus producing kirromycin.
We have cloned and sequenced the tuf1 gene from a kirromycin-producing strain of Streptomyces collinus. The gene encodes a polypeptide of 396 amino acid residues with a molecular weight of 43,849.Expand
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Protein kinase associated with ribosomes phosphorylates ribosomal proteins of Streptomyces collinus.
Protein kinase activity associated with ribosomes of a kirromycin-producing strain of Streptomyces collinus was detected. The enzyme utilizes [gamma-32P]ATP to phosphorylate proteins, yieldingExpand
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Isolation and characterization of Streptomyces aureofaciens protein-synthesis elongation factor Tu in an aggregated state.
The ability of EF-Tu to aggregate spontaneously was employed for the purification of homogeneous EF-Tu . GDP from Streptomyces aureofaciens. The formation of filamentous structures in the aggregatedExpand
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SsrA genes of streptomycetes and association of proteins to the tmRNA during development and cellular differentiation
Transfer‐messenger RNA (tmRNA, 10Sa RNA, ssrA) is bacterial RNA having both tRNA and mRNA properties and playing an essential role in recycling of 70S ribosomes that are stalled on defective mRNA.Expand
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Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor.
The occurrence of phosphorylated proteins in ribosomes of Streptomyces coelicolor was investigated. Little is known about which biological functions these posttranslational modifications mightExpand
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Elongation factor Tu of the extreme thermophilic hydrogen oxidizing bacterium Calderobacterium hydrogenophilum.
Protein synthesis elongation factor Tu has been purified from an extreme thermophilic hydrogen oxidizing bacterium Calderobacterium hydrogenophilum. The molecular mass of EF-Tu. GDP is 51,000. TheExpand
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Characterization offtsZGene and Its Protein Product fromStreptomyces collinusProducing Kirromycin
Abstract The FtsZ protein is required for septation and conversion of aerial mycelium into chains of streptomycete spores. We have cloned and sequenced theftsZgene fromStreptomycesExpand
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