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Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients.
Current theories of CF pathogenesis predict different predisposing "local environmental" conditions and sites of bacterial infection within CF airways. Here we show that, in CF patients withExpand
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A new classification system for chronic lung allograft dysfunction.
Although survival after lung transplantation has improved significantly during the last decade, chronic rejection is thought to be the major cause of late mortality. The physiologic hallmark ofExpand
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An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease.
  • K. Meyer, G. Raghu, +12 authors B. Wood
  • Medicine
  • American journal of respiratory and critical care…
  • 14 December 2012
BACKGROUND The clinical utility of bronchoalveolar lavage fluid (BAL) cell analysis for the diagnosis and management of patients with interstitial lung disease (ILD) has been a subject of debate andExpand
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IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants.
Bronchiolitis obliterans syndrome (BOS), a process of fibro-obliterative occlusion of the small airways in the transplanted lung, is the most common cause of lung transplant failure. We tested theExpand
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Quantitative and qualitative analysis of rhinovirus infection in bronchial tissues.
Although rhinovirus (RV) infections can cause asthma exacerbations and alter lower airway inflammation and physiology, it is unclear how important bronchial infection is to these processes. To studyExpand
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Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive
Heterozygous mutations in four telomere-related genes have been linked to pulmonary fibrosis, but little is known about similarities or differences of affected individuals. 115 patients withExpand
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An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome
Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that is associated with poor survival. The International Society for Heart and Lung Transplantation, AmericanExpand
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Tobramycin solution for inhalation reduces sputum Pseudomonas aeruginosa density in bronchiectasis.
We conducted a placebo-controlled, double-blind, randomized study to evaluate the microbiological efficacy and safety of inhaled tobramycin for treatment of patients with bronchiectasis andExpand
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Neutrophils and low-grade inflammation in the seemingly normal aging human lung
Lung function deteriorates with age and is associated with elastin loss, loss of elastic recoil and decline in diffusing capacity for carbon monoxide. To determine whether increased numbers ofExpand
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Bronchoalveolar lavage as a diagnostic tool.
  • K. Meyer
  • Medicine
  • Seminars in respiratory and critical care…
  • 1 October 2007
Bronchoalveolar lavage (BAL) provides an important diagnostic tool that can facilitate the diagnosis of various diffuse lung diseases. BAL fluid can be analyzed to determine white blood cell (WBC)Expand
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