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- Titus Lanz, Drew Carter, K. Merchant
- Neurobiology of disease
- 2003
Postmortem AD brains exhibit dendritic spine loss in the hippocampus. To determine whether this pathology may be associated with amyloid burden, the present study used the Golgi stain technique to… (More)
- Hilary E Marshall, K. Merchant, Jeremiah Stamler
- FASEB journal : official publication of the…
- 2000
A growing body of evidence suggests that the cellular response to oxidative and nitrosative stress is primarily regulated at the level of transcription. Posttranslational modification of… (More)
- Brian Campbell, K. Merchant
- Brain research
- 2003
Several studies indicate a role for the serotonin 2 subfamily (5-HT(2A), 5-HT(2B), 5-HT(2C)) in mediation of fear and anxiety responses. The current study began to examine the effects of stimulating… (More)
- Thomas A. Lanz, John D. Hosley, Wade J. Adams, K. Merchant
- The Journal of pharmacology and experimental…
- 2004
A previous study by us suggests the utility of cerebrospinal fluid (CSF) and plasma Abeta as biomarkers of beta- or gamma-secretase inhibition. The present study characterized further Abeta… (More)
- Anita Letter, K. Merchant, James W. Gibb, G. R. Hanson
- The Journal of pharmacology and experimental…
- 1987
High doses of methamphetamine (METH) induced 200 to 300% increases in the neurotensin-like immunoreactivity (NTLI) concentrations of the substantia nigra and striatum in rats after a single or… (More)
- David M Stone, K. Merchant, G. R. Hanson, James W. Gibb
- Neuropharmacology
- 1987
In the rat, administration of the psychoactive analog of amphetamine 3,4-methylenedioxymethamphetamine (MDMA), causes selective, pronounced decreases in markers of central serotonergic function. The… (More)
- Shu-Wei Sun, Sheng-Kwei Song, +4 authors John J. Kotyk
- Experimental neurology
- 2005
Using magnetic resonance diffusion tensor imaging (DTI), the present study investigates changes in both gray and white matter in the APPsw transgenic mouse (Tg2576), a model of beta-amyloid plaque… (More)
- K. Merchant, Daniel M. Dorsa
- Proceedings of the National Academy of Sciences…
- 1993
Precise neural mechanisms underlying the pathophysiology and pharmacotherapy of psychotic disorders remain largely unknown. Present studies investigated the effects of various antipsychotic drugs on… (More)
- K. Merchant, Lawrence Bush, James W. Gibb, G. R. Hanson
- Brain research
- 1989
Blockade of dopamine D2 receptors with either the selective antagonist, sulpiride, or the non-selective antagonist, haloperidol, induces 2- to 3-fold increases in the content of neurotensin-like… (More)
- K. Merchant, G. S. Gill, +13 authors Ruth E Tenbrink
- The Journal of pharmacology and experimental…
- 1996
Dopamine D2-like receptors play an important role in the pharmacotherapy of psychotic disorders. Molecular and cellular techniques have identified distinct gene products (D2-long, D2-short, D3 and… (More)