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Differentiation of radial glia from radial precursor cells and transformation into astrocytes in the developing rat spinal cord
Radial glial cell origins and functions have been studied extensively in the brain; however, questions remain relating to their origin and fate in the spinal cord. In the present study, radial gliaExpand
Divergent lineages for oligodendrocytes and astrocytes originating in the neonatal forebrain subventricular zone
Although previous studies have revealed that the prenatal rat ventricular zone contains separate progenitor cells for neurons, astrocytes, and oligodendrocytes during the development of the cerebralExpand
Sexually dimorphic effects of maternal separation stress on corticotrophin-releasing factor and vasopressin systems in the adult rat brain
Neonatal maternal separation has been widely used to model the well‐established causal relationship between stress in early life and the later development of depression. As corticotrophin‐releasingExpand
Radial glial cells: key organisers in CNS development.
Radial glia are elongated bipolar cells present in the CNS during development. Our understanding of the unique roles these cells play has significantly expanded in the last decade. Historically,Expand
Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala
BackgroundMaternal immune activation (MIA) is a risk factor for neurodevelopmental disorders such as autism and schizophrenia, as well as seizure development. The amygdala is a brain region involvedExpand
The regional distribution of myelin oligodendrocyte glycoprotein (MOG) in the developing rat CNS: an in vivo immunohistochemical study
Using an immunohistochemical approach we have characterized the in vivo developmental distribution of myelin oligodendrocyte glycoprotein within the rat CNS. Myelin oligodendrocyte glycoproteinExpand
Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles
Cell-permeable phosphorescent probes enable the study of cell and tissue oxygenation, bioenergetics, metabolism, and pathological states such as stroke and hypoxia. A number of such probes have beenExpand
Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system
Purpose The production of reactive oxygen species (ROS) can lead to oxidative stress, which is a strong contributory factor to many ocular diseases. In this study, the removal of trophic factors isExpand
Morphology and differentiation of radial glia in the developing rat spinal cord
Important events underlying the proper functioning of the central nervous system (CNS) include the production, assembly, and differentiation of appropriate types and numbers of cells duringExpand
The spatial and temporal arrangement of the radial glial scaffold suggests a role in axon tract formation in the developing spinal cord
Radial glial cells serve diverse roles during the development of the central nervous system (CNS). In the embryonic brain, they are recognised as guidance conduits for migrating neuroblasts and asExpand