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Epidemiology of plasmid-mediated quinolone resistance in salmonella enterica serovar typhimurium isolates from food-producing animals in Japan
The PFGE analysis suggested that the already existing S. Typhimurium DT104 on the farm fortuitously acquired the qnrS1 plasmid, which is likely to have contributed to the high prevalence of PMQR in food-producing animals in Japan. Expand
Phylogenetic groups and cephalosporin resistance genes of Escherichia coli from diseased food-producing animals in Japan
The results showed that several types of ESBL were identified and three types of β-lactamase were observed for the first time in E. coli from diseased animals in Japan. Expand
A simple quantitative in vitro macrophage migration assay.
In vitro results showed higher macrophage chemotaxis response against the 'concentrated' cocktails as compared to routine 'diluted' cocktail, and responsiveness was seen better with sodium caseinate cocktail asCompared to oyster glycogen in vitro as well as in vivo. Expand
A comparative study of experimental caecal amoebiasis and the evaluation of amoebicides.
The mouse model appears to be the most useful for primary screening of anti-amoebic compounds, and a new oxadiazole compound, BTI 2405E, was found to have tissue and luminal amoebicidal activity. Expand
Activity of a new oxadiazole compound, against experimental infections with Entamoeba histolytica and Giardia lamblia in animal models.
BTI 2286E is more potent than metronidazole in extra intestinal, intra luminal amoebiasis models and has significant advantages in that it is non-mutagenic in the Ames test and has a shorter duration of effective treatment. Expand
Comparative pharmacokinetics and amoebicidal activity of metronidazole and satranidazole in the golden hamster, Mesocricetus auratus.
The data suggest that higher plasma and liver concentrations of satranidazole and greater intrinsic potency probably contribute to superior amoebicidal activity in the hamster model of hepatic infection. Expand