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Involvement of the Antimicrobial Peptide LL-37 in Human Atherosclerosis
Objective—Antimicrobial peptides are effector molecules of the innate immune system. To understand the function of vascular innate immunity in atherosclerosis, we investigated the role of LL-37, aExpand
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Anti–Heat Shock Protein 60 Autoantibodies Induce Atherosclerosis in Apolipoprotein E–Deficient Mice via Endothelial Damage
Background—Accumulating evidence established a positive association of anti–heat shock protein 60 (HSP60) autoantibodies and the presence of atherosclerosis in humans. However, whether theseExpand
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Association of Serum-Soluble Heat Shock Protein 60 With Carotid Atherosclerosis: Clinical Significance Determined in a Follow-Up Study
Background and Purpose— Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis. In the currentExpand
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Molecular chaperones and heat shock proteins in atherosclerosis.
In response to stress stimuli, mammalian cells activate an ancient signaling pathway leading to the transient expression of heat shock proteins (HSPs). HSPs are a family of proteins serving asExpand
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Evaluation of the Validity of High Serum Antistreptolysin O Titre Only, as an Indication for Tonsillectomy
Serum Antistreptolysin O (ASO) titre is raised when there is infection of any organ of the body, by Group A beta haemolytic streptococci (GABHS), Group C or Group G streptococci [1]. Increased serumExpand
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Sodium Glucose Co-transporter-2 Inhibitor: Benefits beyond Glycemic Control
Type 2 diabetes mellitus (T2DM) is a family of metabolic disorders characterized by hyperglycemia as a consequence of abnormalities in insulin secretion and insulin sensitivity. It affects hundredsExpand
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Vitamin D Receptor Gene Polymorphisms in Indian Children with Idiopathic Nephrotic Syndrome
Abstract Idiopathic nephrotic syndrome (INS) is the most common glomerular disorder of childhood. In the present study we have investigated the prevalence of VDR gene polymorphisms in INS patientsExpand
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Service Quality Gap Measurement in Pharmaceutical Educational Institutes: An Empirical Analysis for Model Development
Perspective: One can observe the sea changes that have been taken place in the Indian pharmaceutical business environment. There are challenges for this section and which is possible to overcome byExpand
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Computer-aided Facial Analysis in Diagnosing Dysmorphic Syndromes in Indian Children
To assess the utility of computer-aided facial analysis in identifying dysmorphic syndromes in Indian children. Fifty-one patients with a definite molecular or cytogenetic diagnosis and recognizableExpand
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