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Generation of Anergic and Potentially Immunoregulatory CD25+CD4 T Cells In Vivo After Induction of Peripheral Tolerance with Intravenous or Oral Antigen1
Immunoregulatory CD25+CD4 T cells are thought to arise from the thymus as a distinct lineage of CD4 T cells specific for self Ags. We used the DO11.10 TCR transgenic adoptive transfer system to show… Expand
Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells
- Christina T Moses, K. M. Thorstenson, S. Jameson, A. Khoruts
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 13 January 2003
T cell antigen receptor (TCR) diversity is a critical feature of adaptive immunity. However, restriction of TCR diversity is a potential risk during immune reconstitution by homeostatic… Expand
Myogenic precursor cells in craniofacial muscles.
Craniofacial skeletal muscles (CskM), including the masticatory (MM), extraocular (EOM) and laryngeal muscles (LM), have a number of properties that set them apart from the majority of skeletal… Expand
A model of suppression of the antigen-specific CD4 T cell response by regulatory CD25+CD4 T cells in vivo.
Despite intense recent interest, the suppressive mechanisms of regulatory CD25+CD4 T cells remain poorly understood. One deficiency in the field is the lack of in vivo models where the effects of… Expand
Intravenous or Oral Antigen Vivo After Induction of Peripheral Tolerance CD 4 T Cells In + Immunoregulatory CD 25 Generation of Anergic and Potentially
Extraocular Muscles Contain More Satellite Cells and More Multipotent Precursor Cells than Limb Muscle
Extraocular Muscle Myogenic Precursor Cells Appear to Be More Resistant to Cell Death Than Cells of Limb Muscles