K. M. Spyer
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Studying rhythmogenesis of breathing: comparison of in vivo and in vitro models
In all mammalian species, breathing is controlled by a neuronal network within the lower brainstem. A component known as the ventral respiratory group produces rhythmic activity, which is transmitted… Expand
Neural mechanisms involved in cardiovascular control during affective behaviour
- K. M. Spyer
- Psychology, Medicine
- Trends in Neurosciences
The changes in respiration and cardiovascular output seen during mammalian defensive behaviour are no longer considered to be the product of simple reflexes. Nuclei in the diencephalon (in… Expand
Endothelins and rat carotid body: autoradiographic and functional pharmacological studies.
- D. Mcqueen, M. Dashwood, V. Cobb, S. Bond, C. Marr, K. M. Spyer
- Biology, Medicine
- Journal of the autonomic nervous system
- 25 June 1995
The effects of ET-1 and ET-3 on ventilation and carotid chemosensory discharge have been studied in rats anaesthetised with pentotarbitone. Autoradiographic studies were also performed in vitro to… Expand
Hypothalamic modulation of laryngeal reflexes in the anaesthetized cat: role of the nucleus tractus solitarii.
- M. S. Dawid-Milner, L. Silva-Carvalho, G. E. Goldsmith, K. M. Spyer
- The Journal of physiology
- 15 September 1995
1. This investigation was initiated because activation of laryngeal afferents, either by electrical stimulation of the superior laryngeal nerve (SLN) or by natural stimulation of receptors in the… Expand
Sensing arterial CO(2) levels: a role for medullary P2X receptors.
ATP has been shown to act as an excitatory neurotransmitter in the central nervous system. In this review, evidence is presented to indicate that when ATP is micro-injected into the ventrolateral… Expand
Cardiorespiratory Interactions in Heart‐Rate Control a
The growing interest in the etiology of the sudden infant death syndrome (SIDS) has led to a reawakening of interest in the subject of the physiological control and organization of cardiorespiratory… Expand
Coexpression of Rat P 2 X 2 and P 2 X 6 Subunits in Xenopus Oocytes
CENTRAL NERVOUS SYSTEM CONTROL OF CARDIOVASCULAR FUNCTION: NEURAL MECHANISMS AND NOVEL MODULATORS
1. Studies are described that indicate that hypothalamic stimulation, at sites eliciting the defence reaction, results in an increase in adenosine levels in both the nucleus tractus solitarius (NTS)… Expand
Inhibition of barosensitive neurones evoked by lobule IXb of the posterior cerebellar cortex in the decerebrate rabbit.
- J. Paton, L. Silva-Carvalho, G. E. Goldsmith, K. M. Spyer
- Chemistry, Medicine
- The Journal of physiology
- 1 August 1990
1. Electrical stimulation of lobule IXb of the posterior cerebellar vermis evoked an increase in heart rate and arterial pressure in the decerebrate rabbit. This pattern of response was followed by a… Expand
Processing of afferent inputs in cardiovascular control.
- K. M. Spyer, S. Donoghue, R. Felder, D. Jordan
- Clinical and experimental hypertension. Part A…
The present report describes the use of an antidromic mapping technique to define the extent and localisation of the afferent projections of the arterial baroreceptors and chemoreceptors to the… Expand