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Subthalamic nucleus deep brain stimulation: Summary and meta‐analysis of outcomes
Subthalamic nucleus (STN) deep brain stimulation (DBS) is currently the most common therapeutic surgical procedure for patients with Parkinson's disease (PD) who have failed medical management.Expand
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Validation of the questionnaire for impulsive‐compulsive disorders in Parkinson's disease
As no comprehensive assessment instrument for impulse control disorders (ICDs) in Parkinson's disease (PD) exists, the aim of this study was to design and assess the psychometric properties of aExpand
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Deep brain stimulation: Postoperative issues
Numerous factors need to be taken into account when managing a patient with Parkinson's disease (PD) after deep brain stimulation (DBS). Questions such as when to begin programming, how to conduct aExpand
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Advanced Parkinson disease treated with rotigotine transdermal system
Background: In patients experiencing motor fluctuations, a major treatment challenge is the reduction of “off” time, particularly upon awakening. Rotigotine (Neupro) is a novel dopaminergic agonistExpand
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Deep brain stimulation: Preoperative issues
Numerous factors need to be taken into account in deciding whether a patient with Parkinson's disease (PD) is a candidate for deep brain stimulation. Patient‐related personal factors including ageExpand
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Neuropathological changes in essential tremor: 33 cases compared with 21 controls.
Despite its being one of the most commonly observed neurological disorders, neuropathological studies of essential tremor (ET) are rare. There have been surprisingly few autopsy studies and evenExpand
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Long-term evaluation of deep brain stimulation of the thalamus.
OBJECT The effects of thalamic deep brain stimulation (DBS) on essential tremor (ET) and Parkinson disease (PD) have been well documented, but there is a paucity of long-term data. The aim of thisExpand
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Practice Parameter: Treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology
Objective:To make evidence-based treatment recommendations for the medical and surgical treatment of patients with Parkinson disease (PD) with levodopa-induced motor fluctuations and dyskinesia. ToExpand
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Quality of life in Essential Tremor Questionnaire (QUEST): development and initial validation.
BACKGROUND/OBJECTIVE Essential tremor (ET) can diminish functioning and quality of life (QOL) but generic QOL measures may be relatively insensitive to ET and its therapies. We sought to develop anExpand
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Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease.
Mitochondrial (mt) impairment, particularly within complex I of the electron transport system, has been implicated in the pathogenesis of Parkinson disease (PD). More than half of mitochondriallyExpand
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