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  • Influence
Generation of C5a by phagocytic cells.
The complement activation product, C5a, is a powerful phlogistic factor. Using antibodies to detect human or rat C5a, incubation at pH 7.4 of human blood neutrophils or rat alveolar macrophages (AMs)Expand
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Role of C5a in Multiorgan Failure During Sepsis1
In humans with sepsis, the onset of multiorgan failure (MOF), especially involving liver, lungs, and kidneys, is a well known complication that is associated with a high mortality rate. Our previousExpand
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Complement-Induced Impairment of Innate Immunity During Sepsis1
This study defines the molecular basis for defects in innate immunity involving neutrophils during cecal ligation/puncture (CLP)-induced sepsis in rats. Blood neutrophils from CLP rats demonstratedExpand
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Protection of innate immunity by C5aR antagonist in septic mice
Innate immune functions are known to be compromised during sepsis, often with lethal consequences. There is also evidence in rats that sepsis is associated with excessive complement activation andExpand
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  • Open Access
A Randomized Prospective Study of Rehabilitation Therapy in the Treatment of Radiation-induced Dysphagia and Trismus
AbstractPurpose:To evaluate the therapeutic effect of rehabilitation therapy on radiation-induced dysphagia and trismus in nasopharyngeal carcinoma (NPC) patients after radiotherapy.Patients andExpand
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Expression and Function of C5a Receptor in Mouse Microvascular Endothelial Cells1
The complement-derived anaphylatoxin, C5a, is a potent phlogistic molecule that mediates its effects by binding to C5a receptor (C5aR; CD88). We now demonstrate specific binding of radiolabeledExpand
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  • Open Access
Subspecies typing of Vibrio parahaemolyticus by pulsed-field gel electrophoresis.
Vibrio parahaemolyticus is one of the most important food-borne pathogens in Taiwan, Japan, and other costal regions. We report on the development of a pulsed-field gel electrophoresis (PFGE) methodExpand
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  • Open Access
Radiation-induced cranial neuropathy in patients with nasopharyngeal carcinoma
GoalThe purpose of the current study was to investigate the long-term characteristics of radiation-induced cranial nerve injury in nasopharyngeal carcinoma (NPC) patients.Patients and methodsWeExpand
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Protective effects of anti‐C5a peptide antibodies in experimental sepsis
We evaluated antibodies to different peptide regions of rat C5a in the sepsis model of cecal ligation and puncture (CLP) for their protective effects in rats. Rabbit polyclonal antibodies wereExpand
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T follicular helper cell diversity and plasticity.
CD4(+) T helper (Th) cells play an instrumental role in orchestrating adaptive immune responses to invading pathogens through their ability to differentiate into specialized effector subsets. Part ofExpand
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