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Systems metabolic engineering of Escherichia coli for L-threonine production
Amino‐acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, weExpand
Metabolic engineering of Escherichia coli for the production of l-valine based on transcriptome analysis and in silico gene knockout simulation
The l-valine production strain of Escherichia coli was constructed by rational metabolic engineering and stepwise improvement based on transcriptome analysis and gene knockout simulation of the inExpand
Enhanced production of bioethanol and ultrastructural characteristics of reused Saccharomyces cerevisiae immobilized calcium alginate beads.
Yeast immobilized on alginate beads produced a higher ethanol yield more rapidly than did free yeast cells under the same batch-fermentation conditions. The optimal fermentation conditions were 30°C,Expand
Enhancement of natural ventilation in buildings using a thermal chimney
A new module was developed for and implemented in the EnergyPlus program for the simulation and determination of the energy impact of thermal chimneys. This paper describes the basic concepts,Expand
Evaluation of anti-inflammatory, antioxidant and anti- nociceptive activities of six Malaysian medicinal plants
The anti-inflammatory, antioxidant and anti-nociceptive properties of six Malaysian medicinal plants, including Carica papaya, Musa acuminata, Oenanthe javanica, Piper sarmentosum, PsophocarpusExpand
Fed‐batch culture of Escherichia coli for L‐valine production based on in silico flux response analysis
We have previously reported the development of a 100% genetically defined engineered Escherichia coli strain capable of producing L‐valine from glucose with a high yield of 0.38 g L‐valine per gramExpand
Energy savings from extended air temperature setpoints and reductions in room air mixing - eScholarship
Large amounts of energy are consumed by air-conditioning systems to maintain tight control of air temperature in rooms--a narrow range of temperature excursion from neutral, and a uniform temperatureExpand
The cooling and heating potential of an earth tube system in buildings
A new module was developed for and implemented in the EnergyPlus program for the simulation of earth tubes. The model was validated against and showed good agreement with both theoretical andExpand
IMPLEMENTATION OF AN EARTH TUBE SYSTEM INTO ENERGYPLUS PROGRAM
A new module was developed for and implemented in the EnergyPlus program for the simulation of earth tubes. This paper describes the basic concepts, assumptions, and algorithms implemented into theExpand
Metabolite essentiality elucidates robustness of Escherichia coli metabolism
Complex biological systems are very robust to genetic and environmental changes at all levels of organization. Many biological functions of Escherichia coli metabolism can be sustained againstExpand
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