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Protein Nanoarrays Generated By Dip-Pen Nanolithography
Dip-pen nanolithography was used to construct arrays of proteins with 100- to 350-nanometer features. These nanoarrays exhibit almost no detectable nonspecific binding of proteins to their passivated… Expand
Phosphoproteomic analysis of human embryonic stem cells.
Protein phosphorylation, while critical to cellular behavior, has been undercharacterized in pluripotent cells. Therefore, we performed phosphoproteomic analyses of human embryonic stem cells (hESCs)… Expand
Guiding stem cell differentiation into oligodendrocytes using graphene-nanofiber hybrid scaffolds.
- S. Shah, P. T. Yin, T. M. Uehara, Sy-Tsong Dean Chueng, Letao Yang, K. Lee
- Materials Science, Medicine
- Advanced materials
- 1 June 2014
Damage to the central nervous system (CNS) from degenerative diseases or traumatic injuries is particularly devastating due the limited regenerative capabilities of the CNS. Among the current… Expand
The use of nanoarrays for highly sensitive and selective detection of human immunodeficiency virus type 1 in plasma
Arrays of antibodies with well-defined feature size and spacing are necessary for developing highly sensitive and selective immunoassays to detect macromolecules in complex solutions. Here we report… Expand
Exocytosis of nanoparticles from cells: role in cellular retention and toxicity.
- Ramin Sakhtianchi, R. Minchin, K. Lee, A. AlKilany, Vahid Serpooshan, M. Mahmoudi
- Chemistry, Medicine
- Advances in colloid and interface science
- 1 December 2013
Over the past decade, nanoparticles (NPs) have been increasingly developed in various biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug delivery, and tissue… Expand
Graphene-encapsulated nanoparticle-based biosensor for the selective detection of cancer biomarkers.
- Sung Myung, Aniruddh Solanki, Cheoljin Kim, J. Park, K. S. Kim, K. Lee
- Advanced materials
Nanomaterials such as silicon nanowires (SiNWs), [ 1 , 2 ] carbon nanotubes (CNTs), [ 3–6 ] and graphene, [ 7,8 ] have gained much attention for use in electrical biosensors due to their nanoscopic… Expand
Nanotechnology for regenerative medicine: nanomaterials for stem cell imaging.
Although stem cells hold great potential for the treatment of many injuries and degenerative diseases, several obstacles must be overcome before their therapeutic application can be realized. These… Expand
Versatile fluorescence resonance energy transfer-based mesoporous silica nanoparticles for real-time monitoring of drug release.
We describe the development of a versatile fluorescence resonance energy transfer (FRET)-based real-time monitoring system, consisting of (a) coumarin-labeled-cysteine tethered mesoporous silica… Expand
A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.
The clinical practice of oncology is being transformed by molecular diagnostics that will enable predictive and personalized medicine. Current technologies for quantitation of the cancer proteome are… Expand
ZnO thin film transistor immunosensor with high sensitivity and selectivity
A zinc oxide thin film transistor-based immunosensor (ZnO-bioTFT) is presented. The back-gate TFT has an on-off ratio of 108 and a threshold voltage of 4.25 V. The ZnO channel surface is… Expand