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Proteoglycans and tumor progression: Janus-faced molecules with contradictory functions in cancer.
MSC, a new benzoquinone-containing natural product with antimetastatic effect.
The results show that the fermented wheat germ extract (MSC) has more than an additive effect and synergistically enhanced the metastasis inhibitory effect of both antineoplastic agents studied till now.
Isolation of a transplantable cell line induced by the MC29 avian leukosis virus.
- A. Langlois, K. Lapis, R. Ishizaki, J. W. Beard, D. Bolognesi
- Biology, MedicineCancer research
- 1 June 1974
The transplantable cell line isolated from a liver tumor induced by theMC29 strain of avian leukosis virus exhibited unusual properties, compared with other MC29 altered cells, and appears to represent a unique target cell for the MC29 virus.
Effect of Avemar and Avemar + vitamin C on tumor growth and metastasis in experimental animals.
- M. Hidvégi, E. Rásó, R. Tömösközi-Farkas, S. Paku, K. Lapis, B. Szende
- MedicineAnticancer research
- 1 July 1998
Avemar proved to have a meaningful immunostimulatory effect and it might be suggested that the observed metastasis-inhibiting effect of this preparation may be mainly due to its immunostIMulatory properties.
Effect of MSC on the immune response of mice.
Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats.
It has been demonstrated for the first time that a wheat germ extract prevents colonic cancer in laboratory animals and is a tentative chemo-preventive agent.
Morphological aspects of angiogenesis in experimental liver metastases.
The dominant type of angiogenesis in liver metastases can be determined by the unique basement membrane architecture of the liver and by the high affinity of 3LL tumor cells to the endothelial side of basement membrane during invasion.
Selection and characterization of human melanoma lines with different liver‐colonizing capacity
- A. Ladányi, J. Tímár, S. Paku, G. Molnar, K. Lapis
- Biology, MedicineInternational journal of cancer
- 15 September 1990
The findings suggest that the selection in the spleen‐liver system did not result in an overall increase in the metastatic potential of the melanoma cells, but rather that it represented an organ‐preferential selection.
Comparative study on Lewis lung tumor lines with 'low' and 'high' metastatic capacity. I. Growth rate, morphology and resistance to host defence.
A highly metastatic variant of liver metastasizing Lewis lung tumor (LLT) has been selected and increased metastasis formation seemed to result from the selection of cells with increased resistance to nonspecific host effector cells.