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  • Carina Strell, K. Lang, Bernd Niggemann, Kurt S. Zaenker, Frank Entschladen
  • Biology, Medicine
  • Cellular and Molecular Life Sciences
  • 2007 (First Published: 1 December 2007)
  • Abstract.The extravasation of leukocytes and tumor cells is a multi-step process with the involvement of various adhesion molecules depending on the three steps rolling, adhesion, and diapedesis. WeContinue Reading
  • Theodore L. Drell, James Joseph, K. Lang, Bernd Niggemann, Kurt S. Zaenker, Frank Entschladen
  • Biology, Medicine
  • Breast Cancer Research and Treatment
  • 2003 (First Published: 1 July 2003)
  • Most patients suffering from breast carcinoma do not die due to the primary tumor but from the development of metastases. Active migration of cancer cells is a prerequisite for development of theseContinue Reading
  • S. Potthoff, Frank Entschladen, Bernd Niggemann, Kurt S. Zaenker, K. Lang
  • Biology, Medicine
  • Breast Cancer Research and Treatment
  • 2006 (First Published: 27 September 2007)
  • The development of a primary tumor as such is not the main cause of death, but is rather the spreading of metastases, which causes over 90% of deaths in cancer patients. This largely depends on theContinue Reading
    The four main cell functions, proliferation, apoptosis, differentiation and migration, are tightly regulated by external signals that initiate intracellular signal transduction pathways and determineContinue Reading