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Infectious cell entry mechanism of influenza virus.
Interaction between influenza virus WSN strain and MDCK cells was studied by using spin-labeled phospholipids and electron microscopy. Envelope fusion was negligibly small at neutral pH but greatlyExpand
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Retarded processing of influenza virus hemagglutinin in insect cells.
When expressed in Spodoptera frugiperda cells by a baculovirus vector, the hemagglutinin of fowl plague virus has been found to contain palmitic acid in covalent hydroxylamine-sensitive linkage,Expand
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Dual Wavelength Imaging Allows Analysis of Membrane Fusion of Influenza Virus inside Cells
ABSTRACT Influenza virus hemagglutinin (HA) is a determinant of virus infectivity. Therefore, it is important to determine whether HA of a new influenza virus, which can potentially cause pandemics,Expand
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Anti-influenza virus activity of Chaenomeles sinensis.
AIM OF THE STUDY This investigation evaluated anti-influenza virus activity of 50% ethanol extract of the fruit of Chaenomeles sinensis K(OEHNE), which is widely used as a traditional ChineseExpand
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The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vector.
The hemagglutinin of fowl plague virus has been expressed in Spodoptera frugiperda (SF) cell cultures using a baculovirus vector. To elucidate the structure of the carbohydrate side chains,Expand
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Expression of the influenza virus haemagglutinin in insect cells by a baculovirus vector.
The insect baculovirus Autographa californica nuclear polyhedrosis virus (AcNPV) has played a major role in studies on the molecular biology of insect DNA viruses. Recently, this system has beenExpand
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Site-specific mutagenesis identifies three cysteine residues in the cytoplasmic tail as acylation sites of influenza virus hemagglutinin.
The hemagglutinin (HA) of influenza virus is a type I transmembrane glycoprotein which is acylated with long-chain fatty acids. In this study we have used oligonucleotide-directed mutagenesis ofExpand
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Synthesis of biologically active influenza virus hemagglutinin in insect larvae.
The hemagglutinin of influenza (fowl plague) virus was expressed in larvae of Heliothis virescens by using recombinant Autographa californica nuclear polyhedrosis virus (AcNPV) as a vector. AnimalsExpand
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Mutations blocking the transport of the influenza virus hemagglutinin between the rough endoplasmic reticulum and the Golgi apparatus.
Mutants ts1 and ts227 of fowl plague virus have a temperature‐sensitive defect in the transport of the hemagglutinin from the rough endoplasmic reticulum to the Golgi apparatus. The primary structureExpand
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Localization of influenza virus proteins to nuclear dot 10 structures in influenza virus-infected cells.
We studied influenza virus M1 protein by generating HeLa and MDCK cell lines that express M1 genetically fused to green fluorescent protein (GFP). GFP-M1 was incorporated into virions produced byExpand
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