• Publications
  • Influence
Metabolites from the Endophytic Fungus Nodulisporium sp. from Juniperus cedre
Seven new metabolites, 3-hydroxy-1-(2,6-dihydroxyphenyl)butan-1-one (1), 1-(2-hydroxy-6-methoxyphenyl)butan-1-one (3), 2,3-dihydro-5-methoxy-2-methylchromen-4-one (6), the dimeric naphthalenesExpand
  • 88
  • 10
ANGUCYCLINES : TOTAL SYNTHESES, NEW STRUCTURES, AND BIOSYNTHETIC STUDIES OF AN EMERGING NEW CLASS OF ANTIBIOTICS
General and recent aspects of chemical syntheses on angucyclinones and selected related natural products are summarized here. In the first part of this review on angucyclines, the chemical reactionExpand
  • 140
  • 3
New mono- and dimeric members of the secalonic acid family: blennolides A-G isolated from the fungus Blennoria sp.
Blennolides A-G (2-8), seven unusual chromanones, were isolated together with secalonic acid B (1) from Blennoria sp., an endophytic fungus from Carpobrotus edulis. This is the first reportedExpand
  • 123
  • 2
Prismatomerin, a New Iridoid from Prismatomeris tetrandra. Structure Elucidation, Determination of Absolute Configuration, and Cytotoxicity
A new complex iridoid, prismatomerin (1), has been isolated from the leaves of Prismatomeris tetrandra, together with the known glucoside gaertneroside (4). The structures of 1 and 4 were determinedExpand
  • 27
  • 2
Denbinobin inhibits nuclear factor-kappaB and induces apoptosis via reactive oxygen species generation in human leukemic cells.
Denbinobin, a 1,4-phenanthrenequinone firstly isolated from the stems of Dendrobium moniliforme (Shi-Hu in Chinese medicine), has been reported to exhibit anti-tumoral and anti-inflammatoryExpand
  • 52
  • 1
Xanthones and oxepino[2, 3-b]chromones from three endophytic fungi.
Three new metabolites, microsphaeropsones A-C (1-3) with a unique oxepino[2,3-b]chromen-6-one (ring-enlarged xanthone) skeleton, were isolated from the endophytic fungus Microsphaeropsis species,Expand
  • 60
  • 1
Denbinobin, a naturally occurring 1,4-phenanthrenequinone, inhibits HIV-1 replication through an NF-kappaB-dependent pathway.
Anthraquinones and structurally related compounds have been recently shown to exert antiviral activities and thus exhibit a therapeutic potential. In this study we report the isolation of theExpand
  • 28
  • 1
Microsphaerol and Seimatorone: Two New Compounds Isolated from the Endophytic Fungi, Microsphaeropsis sp. and Seimatosporium sp.
A new polychlorinated triphenyl diether named microsphaerol (1), has been isolated from the endophtic fungus Microsphaeropsis sp. An intensive phytochemical investigation of the endophytic fungusExpand
  • 11
  • 1
Antiplasmodial activity of compounds from Drypetes gerrardii
0009-3130/12/4802-0339 2012 Springer Science+Business Media, Inc. 1) Department of Chemistry, Kenyatta University, P.O. Box 43844-00100, Nairobi, Kenya; 2) Department of Chemistry, UniversitatExpand
  • 6
  • 1