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Large-scale identification of N-terminal peptides in the halophilic archaea Halobacterium salinarum and Natronomonas pharaonis.
Characterization of protein N-terminal peptides supports the quality assessment of data derived from genomic sequences (e.g., the correct assignment of start codons) and hints to in vivo N-terminalExpand
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Archaeal N-terminal protein maturation commonly involves N-terminal acetylation: a large-scale proteomics survey.
We present the first large-scale survey of N-terminal protein maturation in archaea based on 873 proteomically identified N-terminal peptides from the two haloarchaea Halobacterium salinarum andExpand
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Sequencing platform and library preparation choices impact viral metagenomes
BackgroundMicrobes drive the biogeochemistry that fuels the planet. Microbial viruses modulate their hosts directly through mortality and horizontal gene transfer, and indirectly by re-programmingExpand
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The low molecular weight proteome of Halobacterium salinarum.
Systematic investigation of low molecular weight proteins (LMW, below 20 kDa) in the archaeon Halobacterium salinarum resulted in a 6-fold enhancement of the identification rate, reaching 35% of theExpand
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Microbial Diversity and Resistance to Copper in Metal-Contaminated Lake Sediment
Contamination of habitats with heavy metals has become a worldwide problem. We describe herein the analysis of lake sediment contaminated with high concentrations of copper as a consequence of mineExpand
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The science case for an orbital mission to Uranus: exploring the origins and evolution of ice giant planets
Giant planets helped to shape the conditions we see in the Solar System today and they account for more than 99% of the mass of the Sun's planetary system. They can be subdivided into the Ice GiantsExpand
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Life‐style changes of a halophilic archaeon analyzed by quantitative proteomics
Quantitative proteomics based on isotopic labeling has become the method of choice to accurately determine changes in protein abundance in highly complex mixtures. Isotope‐coded protein labelingExpand
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Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)
The yeast fatty acid synthase (FAS) is a barrel-shaped 2.6 MDa complex. Upon barrel-formation, two multidomain subunits, each more than 200 kDa large, intertwine to form a heterododecameric complexExpand
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Genome-wide proteomics of Natronomonas pharaonis.
The aerobic, haloalkaliphilic archaeon Natronomonas pharaonis is able to survive in salt-saturated lakes of pH 11. According to genome analysis, the theoretical proteome consists of 2843 proteins. ToExpand
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MUSE – Mission to the Uranian system: Unveiling the evolution and formation of ice giants
This paper is the result of a study carried out during the Alpbach Summer School 2012 “Exploration of the icy planets and their systems” and a one-week follow-up meeting in Graz, Austria. Expand
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