Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins
- F. Ruiz-Perez, R. Wahid, J. Nataro
- BiologyProceedings of the National Academy of Sciences
- 18 July 2011
Pic, a class 2 SPATE protein produced by Shigella flexneri 2a, uropathogenic and enteroaggregative Escherichia coli strains, targets a broad range of human leukocyte adhesion proteins, suggesting that the class-2 SPATEs represent unique immune-modulating bacterial virulence factors.
Effect of magnetic fields on tumor growth and viability.
The results showed that exposure of the mice to magnetic fields for 360 min daily for as long as 4 wk suppressed tumor growth, which supports further exploration of the potential of magnetic fields in cancer therapeutics, either as adjunct or primary therapy.
Association between Moderate-to-Severe Diarrhea in Young Children in the Global Enteric Multicenter Study (GEMS) and Types of Handwashing Materials Used by Caretakers in Mirzapur, Bangladesh
- Kelly K Baker, Fahmida Dil Farzana, M. Levine
- MedicineAmerican Journal of Tropical Medicine and Hygiene
- 2 July 2014
Washing hands with ash is a prevalent behavior in Mirzapur and may help diminish transmission of diarrheal pathogens to children, and contact with ash and water reduced concentrations of bacterial enteropathogens, without mechanical scrubbing.
Escherichia coli O157:H7 infection in Dutch belted and New Zealand white rabbits.
Evidence is provided that both breeds of rabbits are susceptible to E. coli O157:H7 infection and that both may be useful models for investigating EHEC infections of humans, and both breeds developed clinical signs of disease and intestinal lesions after experimental infection.
Disseminated Simian Varicella Virus Infection in an Irradiated Rhesus Macaque (Macaca mulatta)
Analysis indicated that subclinical reactivation of latent SVV from an asymptomatic irradiated monkey likely led to disseminated varicella in the seronegative irradiatedmonkey, and support the usefulness of SVV infection as a model for human varICElla-zoster virus infection, particularly virus reactivation after gamma-irradiation.
Protective effect of inositol hexaphosphate against UVB damage in HaCaT cells and skin carcinogenesis in SKH1 hairless mice.
- Kendra A. Williams, K. Kolappaswamy, L. Detolla, I. Vucenik
- Biology, MedicineComparative medicine
- 1 February 2011
Inositol hexaphosphate (IP6), an antioxidant, is a naturally occurring polyphosphorylated carbohydrate that has shown a strong anticancer activity in several experimental models and it is found that IP6 counteracts the harmful effects of UVB irradiation and increases the viability and survival ofUVB-exposed cells.
Effect of inositol hexaphosphate on the development of UVB-induced skin tumors in SKH1 hairless mice.
Results show that IP6 has an antiphotocarcinogenic effect and can protect against UVB-induced tumor formation, and significantly decreased tumor incidence and tumor multiplicity.
Outbreak of pathogenic Escherichia coli in an outdoor‐housed non‐human primate colony
- K. Kolappaswamy, J. Nazareno, W. P. Porter, H. Klein
- Medicine, BiologyJournal of medical primatology
- 1 April 2014
Pathogenic Escherichia coli has been identified as an etiologic agent in humans causing acute diarrhea or even death but has been rarely reported in non‐human primates (NHP). An outbreak of diarrhea…
Methicillin-resistant Staphylococcus non-aureus infection in an irradiated rhesus macaque (Macaca mulatta).
- K. Kolappaswamy, S. Shipley, I. Tatarov, L. Detolla
- Medicine, BiologyJournal of the American Association for…
- 1 May 2008
The importance of the occupational risk of methicillin-resistant Staphylococcus non-aureus to research and animal care staff in a research animal facility setting is underscored.