K. Koepfli

Publications96
h-index32
Citations8,313
Highly Influential Citations512
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • S. O'Brien
  • 830 Publications • 72,453 Citations
  • R. Wayne
  • 376 Publications • 34,610 Citations
  • Guojie Zhang
  • 252 Publications • 25,710 Citations
  • O. Ryder
  • 325 Publications • 23,265 Citations
  • Publications
  • Influence
Genome sequence, comparative analysis and haplotype structure of the domestic dog
TLDR
A high-quality draft genome sequence of the domestic dog is reported, together with a dense map of single nucleotide polymorphisms (SNPs) across breeds, to shed light on the structure and evolution of genomes and genes. Expand
Whole-genome analyses resolve early branches in the tree of life of modern birds
TLDR
A genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves recovered a highly resolved tree that confirms previously controversial sister or close relationships and identifies the first divergence in Neoaves, two groups the authors named Passerea and Columbea. Expand
Multigene phylogeny of the Mustelidae: Resolving relationships, tempo and biogeographic history of a mammalian adaptive radiation
TLDR
Using Bayesian dating techniques, phylogenetic and dating analyses suggest that mustelid diversification may have been spurred by a combination of faunal turnover events and diversification at lower trophic levels, ultimately caused by climatically driven environmental changes. Expand
Molecular systematics of the Canidae.
TLDR
A combined analysis of the mtDNA data and published morphological data provides unexpected support for a monophyletic South American canidae clade, although the homogeneity partition tests indicate significant heterogeneity between the two data sets. Expand
A new phylogenetic marker, apolipoprotein B, provides compelling evidence for eutherian relationships.
TLDR
Maximum likelihood and Bayesian analyses of both data sets provide support for the superordinal clades Boreoeutheria, Euarchontoglires, Laurasiatheria, Xenarthra, Afrotheria, and Ostentoria, as well as for the monophyly of the orders Eulipotyphla, Primates, and Rodentia, all of which have recently been questioned. Expand
Complete Mitochondrial Genomes of Ancient Canids Suggest a European Origin of Domestic Dogs
TLDR
The findings imply that domestic dogs are the culmination of a process that initiated with European hunter-gatherers and the canids with whom they interacted, and molecular dating suggests an onset of domestication there 18,800 to 32,100 years ago. Expand
Pattern and timing of diversification of the mammalian order Carnivora inferred from multiple nuclear gene sequences.
TLDR
This study investigated the phylogenetic relationships among carnivoran families, and performed molecular dating analyses of the inferred nodes, leading to consistent and robust resolution of all supra-familial nodes in the carnivoran tree. Expand
Extensive population genetic structure in the giraffe
TLDR
There are at least six genealogically distinct lineages of giraffe in Africa, with little evidence of interbreeding between them, and such extreme genetic subdivision within a large vertebrate with high dispersal capabilities is unprecedented and exceeds that of any other large African mammal. Expand
Phylogeny of the Procyonidae (Mammalia: Carnivora): molecules, morphology and the Great American Interchange.
TLDR
The findings, which are in strong disagreement with prior fossil and morphology-based assessments of procyonid relationships, reemphasize the morphological and ecological flexibility of these taxa and suggest convergence associated with similar lifestyles and diets rather than ancestry. Expand
Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates
TLDR
A protein structural analysis was employed to qualitatively assess whether amino acid changes at variable residues would be likely to disrupt ACE2/SARS-CoV-2 binding, and found the number of predicted unfavorable changes significantly correlated with the binding score. Expand
...
1
2
3
4
5
...