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An improved synthesis of 4-deoxy-4-fluoro-d-galactopyranosyl derivatives
Total Synthesis of the Macrolide Antitumor Antibiotic Lankacidin C
Ring closing metathesis in organic synthesis: Evolution of a high speed, solid phase method for the preparation of β-turn mimetics
Enantioselective total synthesis of lankacidin C
General Preparation of 7-Substituted 4-Chromanones: Synthesis of a Potent Aldose Reductase Inhibitor
A second generation solid phase approach to Freidinger lactams: Application of Fukuyama's amine synthesis and cyclative release via ring closing metathesis
Solid phase heterocyclic synthesis via ring closing metathesis: Traceless linking and cyclative cleavage through a carbon-carbon double bond☆
Preparation of pyrrolidine-based PDE4 inhibitors via enantioselective conjugate addition of alpha-substituted malonates to aromatic nitroalkenes.
This sequence was used for the preparation of the PDE4 inhibitor IC86518 and provides pyrrolidinones with two contiguous stereocenters, one of which is quaternary.
The SAR of UK-78,282 : A novel blocker of human T cell Kv1.3 potassium channels