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Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats.
The endothelium-dependent vascular relaxation to acetylcholine (ACh) in spontaneously hypertensive rats (SHR) may be impaired because of an imbalance of endothelium-derived relaxing factor andExpand
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Age and Hypertension Promote Endothelium‐Dependent Contractions to Acetylcholine in the Aorta of the Rat
This study was undertaken to compare age-related changes in endothelium-dependent vascular responses in both hypertensive and normotensive rats. Aorta from normotensive Wistar-Kyoto (WKY) rats andExpand
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Ageing suppresses endothelium‐dependent relaxation and generates contraction mediated by the muscarinic receptors in vascular smooth muscle of normotensive Wistar‐Kyoto and spontaneously hypertensive
We evaluated the effects of ageing and hypertension on endothelium-dependent relaxation and contraction of vascular smooth muscles. Aortic rings with and without endothelium from normotensiveExpand
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Control of Maximum Rates of Glycolysis in Rat Cardiac Muscle
The maximum rate of glucose utilization by isolated rat hearts was approximately 16 /unol/g dry weight per minute. This rate was observed in aerobic hearts that were developing high levels ofExpand
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Age-related changes in endothelium-dependent hyperpolarization in the rat mesenteric artery.
This study was designed to determine the age-related changes in the endothelium-dependent hyperpolarization to acetylcholine (ACh) and its contribution to relaxation in the isolated mesenteric arteryExpand
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Hypertension and ageing impair acetylcholine‐induced vasodilation in rats
Objective To investigate the influence of hypertension and ageing on the in vivo effect of acetylcholine on blood pressure and regional vascular conductance and the inhibitory effect ofExpand
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Plasma normetanephrine: a biochemical marker of sympathetic nerve function in man.
Abstract The concentration of the catecholamines in plasma are regarded by many investigators as biochemical markers of sympathoadrenal activity in man. This study was designed to: 1) assess theExpand
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Kinetics of pulmonary gas exchange during and while recovering from exercise in patients after anterior myocardial infarction.
The effect of exercise intensity on gas exchange kinetics was investigated during exercise and recovery, as well as the relationship between the kinetics during exercise and recovery. Twenty-threeExpand
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Mechanism of pyruvate dehydrogenase activation by increased cardiac work.
The effects of increased cardiac work, pyruvate and insulin on the state of pyruvate dehydrogenase (PDH) activation and rate of pyruvate decarboxylation was studied in the isolated perfused ratExpand
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Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium.
The present study examined age-related changes in the vascular relaxation response to adenine nucleotides in hypertensive and normotensive rats. Aortic ring segments from normotensive Wistar-KyotoExpand
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