Effects of bile salts on the lovastatin pharmacokinetics following oral administration to rats
In conclusion, the addition of bile salts to lovastatin could enhance drug bioavailabilities, however, too high concentrations of biles salts could decrease bioavailsabilities of lovastirin.
Pharmacokinetic evaluation of formulated levodopa methyl ester nasal delivery systems
The results suggest that LDME nasal powder formulations would be useful delivery systems of l-dopa to the brain.
Effects of vehicles on the percutaneous absorption of donepezil hydrochloride across the excised hairless mouse skin
IPA-containing solution formulations and DGME-PGML (40: 60)-containing PSA TDS were found to be favorable candidates for donepezil transdermal delivery.
Pharmacokinetic evaluation of formulated levodopa methyl ester nasal delivery systems
The results suggest that LDME nasal powder formulations would be useful delivery systems of l-dopa to the brain.
Analysis of Gender Differences in Physician’s Desk Reference
It is necessary to establish domestic policies for drug approval and use which reflects gender-based differences through sufficient researches throughsufficient researches.
Review of Gender Differences in Medicine and Primary Factors Resulting in Gender Differences
- Hyun Ju Kim, J. Choi, H. Lee
- Biology, Medicine
- 30 September 2010
It has been reported that females experience more adverse reactions such as coughing, tachycardia, nausea, vomiting, rash, hypersensitivity, hepatotoxicity, and metabolic disorder after taking cardiovascular, central nervous system acting and antiviral agents, and in order to provide optimal drug dosage regimens both in male and female, gender differences in pharmacokinetics, pharmacodynamics, and adverse drug reactions must be considered.