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Structure of pestalotan, a highly branched (1----3)-beta-D-glucan elaborated by Pestalotia sp. 815, and the enhancement of its antitumor activity by polyol modification of the side chains.
The water-soluble, SD-pestalotan polyol, having a molecular weight of 4.7 X 10(5), exhibited remarkable antitumor activities against both allogeneic and syngeneic, mouse-implanted tumors, at small dosages (1-5 mg/kg for 10 days) by intraperitoneal administration.
Syntheses and Catalytic Actions of Self-Vesicle and Micelle-Forming Enzyme Models of Hydrolase
Vesicle-forming catalysts, N- {1- [(3-acety1-4-didodecylcarbamoyl-2-thiazolidinyl) manno-tetra-hydroxybutyl] carbonyl} -L-histidine and-L-histidyl-L-alanine, and micelle-forming catalysts, N- {4-
Syntheses and Catalytic Actions of Self-Micelle-Forming Hydrolase Models
Hydrolase model catalysts, N-alkyl-Nα-[2-(D-polyhydroxypentyl)-3-acetyl-4-thiazolidinylcarbonyl]-L-histidinamide (acyclic-type catalyst) and N-(N-alkanoyl-L-nistidyl)-β-D-glucosamine (cyclic-type
Production of polyamic acid
PURPOSE: To obtain a high-molecular-weight polyamic acid in good reproducibility by using an inorganic salt as a polyamide formation catalyst in the reaction for preparing the polyamic acid.