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Epidemiology of paramphistomosis in domestic ruminants in different districts of Punjab and other adjoining areas
TLDR
An epidemiological study was carried out under the aegis of National Agricultural Technology Project from August 2000 to September 2003 and a total of 3,335 faecal samples of domestic ruminants were examined for the presence of paramphistome eggs from different districts of Punjab and other areas of adjoining states.
Amniotic fluid embolism
TLDR
Treatment is mainly supportive, but exchange transfusion, extracorporeal membrane oxygenation, and uterine artery embolization have been tried from time to time.
Myocilin gene implicated in primary congenital glaucoma
TLDR
A possible role of MYOC in PCG, which might be mediated via digenic interaction with CYP1B1 and/or an yet unidentified locus associated with the disease, is suggested.
Glaucoma-associated CYP1B1 mutations share similar haplotype backgrounds in POAG and PACG phenotypes.
TLDR
The results demonstrate an involvement of CYP1B1 in a proportion of POAG and PACG cases and the similar haplotype background of these mutations is indicative of their common origin across multiple glaucoma phenotypes.
Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway
TLDR
The studies indicated that upregulation of PTEN by hUCBSC in glioma cells and in the nude mice tumors downregulated Akt and PI3K signaling pathway molecules resulted in the inhibition of migration as well as wound healing property of the gliomas cells.
Mutation spectrum of the CYP1B1 gene in Indian primary congenital glaucoma patients.
TLDR
This study provides a mutation spectrum of CYP1B1 causing primary congenital glaucoma in Indian populations that has implications in devising molecular diagnostics for rapid screening and Genotype-phenotype correlation indicated variable prognosis that could be due to the type of mutation, leading to alteration of CyP1 B1 protein.
Globally, CYP1B1 mutations in primary congenital glaucoma are strongly structured by geographic and haplotype backgrounds.
TLDR
A global perspective on the distribution and evolution of CYP1B1 mutations in primary congenital glaucoma (PCG) worldwide is obtained to gain evolutionary insights and the strong association of specific haplotypes with some predominant CYP 1B 1 mutations underlying PCG and the observed geographical clustering are useful for predictive testing.
Primary Congenital Glaucoma and the Involvement of CYP1B1
TLDR
Insight is provided into PCG pathogenesis and the potential role of CYP1B1 in the disease phenotype and a new locus (GLC3D) harboring the LTBP2 gene has been characterized in developmental glaucoma.
Comparative evaluation of subclavian vein catheterisation using supraclavicular versus infraclavicular approach
TLDR
The SC approach of SCV catheterisation is comparable to IC approach in terms of landmarks accessibility, success rate and rate of complications.
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