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Specific inactivation of prolyl 4-hydroxylase and inhibition of collagen synthesis by oxaproline-containing peptides in cultured human skin fibroblasts.
TLDR
Peptides containing the unphysiological amino acid 5-oxaproline (Opr) inactivate prolyl 4-hydroxylase in cultured human skin fibroblasts, with peptide I being about twice as potent as peptide II. Expand