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Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction.
BACKGROUND Transforming growth factor-beta (TGF-beta) has been implicated in the development of renal fibrosis induced by unilateral ureteral obstruction (UUO). However, there is little informationExpand
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A prospective study on the use of mycophenolate mofetil in children with cyclosporine-dependent nephrotic syndrome
Cyclosporine A (CsA) has relieved children with steroid-dependent nephrotic syndrome (NS) from steroid toxicity. However, most patients frequently relapse again when CsA is withdrawn, resulting inExpand
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Angiotensin converting enzyme gene polymorphism in primary vesicoureteral reflux
Abstract  We studied the insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE) gene in 78 patients with primary vesicoureteral reflux (VUR), and examined renal function byExpand
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A young child with pseudohypoaldosteronism type II by a mutation of Cullin 3
BackgroundPseudohypoaldosteronism type II (PHA II), also referred to as Gordon syndrome, is a rare renal tubular disease that is inherited in an autosomal manner. Though mutations in WNK1 and WNK4Expand
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Steroid Pulse Therapy for Children With Intravenous Immunoglobulin Therapy–Resistant Kawasaki Disease: A Prospective Study
Patients with Kawasaki disease (KD) who did not respond to the initial IVIG are known to have higher risk for developing coronary arterial lesions (CALs). Our aim is to clarify whether patients withExpand
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Focal segmental glomerulosclerosis in a boy with Dent-2 disease
Sirs, Proximal tubular dysfunction is, in general, more common when the nephrotic syndrome is associated with focal segmental glomerulosclerosis (FSGS) than with minimal-change nephrotic syndrome.Expand
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Pathogenesis of childhood idiopathic nephrotic syndrome: a paradigm shift from T-cells to podocytes
BackgroundNephrotic syndrome is the most common cause of kidney disease in children, but its pathogenesis remains unclear. This article reviews the novel aspects of the mechanisms underlying massiveExpand
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B-type natriuretic peptide for assessment of haemodynamically significant patent ductus arteriosus in premature infants
Haemodynamically significant patent ductus arteriosus (hsPDA) is frequently observed in premature infants. This study was conducted to explore whether the blood BNP can be a valuable biomarker toExpand
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Increased urinary angiotensinogen is an effective marker of chronic renal impairment in very low birth weight children
BackgroundRecent advancements in perinatal and neonatal care have increased the survival of preterm infants with lower birth weight and very low birth weight (VLBW; < 1,500 g) infants. Such infantsExpand
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Predictive value of IgE/IgG4 antibody ratio in children with egg allergy
BackgroundThe aim of this study was to investigate the role of specific IgG4 antibodies to hen’s egg white and determine their utility as a marker for the outcome of oral challenge test in childrenExpand
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