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Isolation of an antiviral polysaccharide, nostoflan, from a terrestrial cyanobacterium, Nostoc flagelliforme.
TLDR
Besides anti-HSV-1 activity, nostoflan showed potent antiviral activities against HSV-2, human cytomegalovirus, and influenza A virus, but no activity against adenovirus and coxsackie virus was observed. Expand
Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection.
TLDR
Results suggested that oral intake of the fucoidan might take the protective effects through direct inhibition of viral replication and stimulation of both innate and adaptive immune defense functions. Expand
Anti-herpes simplex virus target of an acidic polysaccharide, nostoflan, from the edible blue-green alga Nostoc flagelliforme.
TLDR
The results indicated that the inhibition of virus binding to but not penetration into host cells was responsible for the antiherpetic effect induced by nostoflan. Expand
Loss of Branched O-Mannosyl Glycans in Astrocytes Accelerates Remyelination
TLDR
Together, branched O-mannosyl glycans in the corpus callosum in the brain are a necessary component of remyelination inhibition in the cuprizone-induced demyelinations model, suggesting that modulation of O- Mannosyl glycan glycans is a likely candidate for therapeutic strategies. Expand
[Structure and antiviral activity of an acidic polysaccharide from an edible blue-green alga, Nostoc flagelliforme].
TLDR
NSF showed potent antiviral activities against several enveloped viruses including herpes simplex virus type 1, type 2 (HSV-1, HSV-2), human cytomegalovirus, and influenza A virus (IFV), and the mortality of mice was significantly decreased. Expand
Effects of Intrathecal Injection of the Conditioned Medium from Bone Marrow Stromal Cells on Spinal Cord Injury in Rats.
TLDR
Activation of the intrinsic ability of the spinal cord to regenerate by the injection of neurotrophic factors such as BMSC-CM is considered to be a safe and preferable method for the clinical treatment of SCI. Expand
Identification of Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) as a Regulator of N-Acetylglucosaminyltransferase GnT-IX (GnT-Vb)*
TLDR
The existence of an endogenous inhibitory factor for GnT-IX that functions as a key regulator for Gnt-IX enzymatic activity in Neuro2a (N2a) cells is demonstrated and a novel regulatory system for the cellular glycosylation process is proposed. Expand
Locomotor improvement of spinal cord-injured rats through treadmill training by forced plantar placement of hind paws
TLDR
Failed treadmill training by plantar placement of the hind paws promoted the behavioral and histological improvement of rats with SCI. Expand
Points regarding cell transplantation for the treatment of spinal cord injury
Transplantation of somatic cells, including bone marrow stromal cells (BMSCs), bone marrow mononuclear cells (BMNCs), and choroid plexus epithelial cells (CPECs), enhances the outgrowth ofExpand
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