Endoglin is a suitable target for efficient imaging of solid tumors: in vivo evidence in a canine mammary carcinoma model.
- E. Fonsatti, A. Jekunen, M. Maio
- BiologyClinical Cancer Research
- 1 May 2000
The present data suggest that targeting of CD105 on tumor-associated blood vessels may represent a new strategy for in vivo imaging of solid malignancies, regardless of their histological origin.
Imaging of olfactory neuroblastoma--an analysis of 17 cases.
- K. Kairemo, A. Jekunen, M. Kestilä, H. Ramsay
- MedicineAuris, nasus, larynx
- 1 May 1998
Measuring visceral adipose tissue content from contrast enhanced computed tomography.
- T. Vehmas, K. Kairemo, M. Taavitsainen
- MedicineInternational journal of obesity and related…
- 1 June 1996
VAT content may be retrospectively quantified from routine abdominal CT images, but the unfavorable effects of i.v. contrast administration on measurements must be taken into account.
Elimination of Stabilised Hyaluronan from the Knee Joint in Healthy Men
- U. Lindqvist, V. Tolmachev, K. Kairemo, G. Åström, E. Jonsson, H. Lundqvist
- Medicine, BiologyClinical Pharmacokinetics
- 2002
The elimination kinetics of 131I-labelled NASHA from the human knee joint were described by three distinct phases, with half-times of 1.5 hours,1.5 days and 4 weeks, which likely reflects the true half-life of NASHA following intra-articular injection since the labelling method used causes minimal modification of hyaluronan.
Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8+ T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian…
- L. Vassilev, T. Ranki, S. Pesonen
- Medicine, BiologyOncoimmunology
- 1 April 2015
A case of a 38-year-old female with Stage 3 metastatic micropapillary serous carcinoma of the ovary treated with a granulocyte-macrophage colony stimulating factor-expressing oncolytic adenovirus, Ad5/3-D24-GMCSF (ONCOS-102), which resulted in progressive infiltration of CD8+ lymphocytes into the tumor and concomitant systemic induction of several tumor-specific T-cells.
Radioimmunodetection and radioimmunotherapy of head and neck cancer.
- P. K. Börjesson, E. Postema, G. V. van Dongen
- Biology, MedicineOral Oncology
- 1 September 2004
Scintigraphic assessment of slow transit constipation with special reference to right‐ or left‐sided colonic delay
- E. Lundin, U. Karlbom, W. Graf
- MedicineColorectal Disease
- 1 November 2004
A scintigraphic method to assess colonic transit with special reference to right‐ or left‐sided delay is evaluated and it is shown that this method can be used to identify segmental colonic motor dysfunction.
131I radioconjugated antibodies for the locoregional radioimmunotherapy of high-grade malignant glioma--phase I and II study.
- P. Riva, G. Franceschi, K. Kairemo
- Medicine, BiologyActa oncologica
- 1999
It is concluded that fractionated LR-RIT can be safely performed, with promising results especially in patients with minimal disease, and in cases with less aggressive diseases: oligodENDroglioma, anaplastic oligodendrogliomas and anaplastics astrocytoma.
Scintigraphy in prediction of the salivary gland function after gland-sparing intensity modulated radiation therapy for head and neck cancer.
- M. Tenhunen, J. Collan, K. Saarilahti
- MedicineRadiotherapy and Oncology
- 1 May 2008
Immunolymphoscintigraphy and immunoscintigraphy of ovarian and fallopian tube cancer using F(ab')2 fragments of monoclonal antibody OC 125.
- P. Lehtovirta, K. Kairemo, K. Liewendahl, M. Seppälä
- Medicine, BiologyCancer Research
- 1 February 1990
Combined results of ILS and immunoscintigraphy in 16 surgically verified cases indicated a true positive finding in 9 patients, true negative finding in 5, false positive in one, and false negative in 1, demonstrating that an elevated serum CA 125 level does not preclude successful radioimmunodetection.
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