Share This Author
Lipid rafts control human melanoma cell migration by regulating focal adhesion disassembly.
Actin Polymerization Negatively Regulates p53 Function by Impairing Its Nuclear Import in Response to DNA Damage
It is shown that DNA damage induces both actin polymerization and p53 accumulation, and it is proposed that actin Polymerization might be a factor participating in the process of orchestrating p53 function in response to DNA damage.
Identification of nucleolin as a lipid-raft-dependent β1-integrin-interacting protein in A375 cell migration
It is demonstrated that nucleolin is a critical lipid-raft-dependent β1-integrin-interacting protein in A375 cell spreading and migration on fibronectin.
Lipid raft regulates the initial spreading of melanoma A375 cells by modulating β1 integrin clustering.
S-acylation regulates the trafficking and stability of the unconventional Q-SNARE STX19
The Q-SNARE STX19 is S-acylated by Golgi-localised S-ACYltransferases, and this lipidation targets the protein to MICAL-L1-positive tubular recycling endosomes and also protects it from proteasomal degradation.
c-Abl Kinase Is a Regulator of αvβ3 Integrin Mediated Melanoma A375 Cell Migration
It is shown that c-Abl kinase is involved in A375 cell migration mediated by αvβ3 integrin in response to PDGF stimulation, and a novel and critical role is uncovered in αv β3 integrins mediated melanoma cell migration.
Lipid Raft Is Required for PSGL-1 Ligation Induced HL-60 Cell Adhesion on ICAM-1
It is reported that ligation of PSGL-1 on HL-60 cells activates β2 integrin, for which lipid raft integrity and Syk activation are responsible, which shed new light on the mechanisms that connect leukocyte initial rolling with subsequent adhesion.
Role of NS2 specific RNA binding and phosphorylation in liquid–liquid phase separation and virus assembly
It is shown that NS2 undergoes LLPS that is dependent on protein phosphorylation and RNA-binding and that LLPS occurrence is accompanied by a change in protein secondary structure.
- K. K. Ampah
It’s time to dust off the gloves and get ready for the cold weather.