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Stonustoxin Is a Novel Lethal Factor from Stonefish (Synanceja horrida) Venom
Stonustoxin (SNTX) is a multifunctional lethal protein isolated from venom elaborated by the stonefish, Synanceja horrida. It comprises two subunits, termed α and β, which have respective molecularExpand
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MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion
Background and Purpose— Several hundred small RNAs called microRNAs (miRNAs) have been identified and characterized from various organisms, including humans. In humans, some of these miRNAs have beenExpand
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Tamapin, a Venom Peptide from the Indian Red Scorpion (Mesobuthus tamulus) That Targets Small Conductance Ca2+-activated K+ Channels and Afterhyperpolarization Currents in Central Neurons*
The biophysical properties of small conductance Ca2+-activated K+ (SK) channels are well suited to underlie afterhyperpolarizations (AHPs) shaping the firing patterns of a conspicuous number ofExpand
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A new potassium channel toxin from the sea anemone Heteractis magnifica: isolation, cDNA cloning, and functional expression.
A new potassium channel toxin, HmK, has been isolated from the sea anemone Heteractis magnifica. It inhibits the binding of [125I]-alpha-dendrotoxin (a ligand for voltage-gated K channels) to ratExpand
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Highly permeable and selective pore-spanning biomimetic membrane embedded with aquaporin Z.
A highly permeable yet highly selective pore-spanning biomimetic membrane embedded with aquaporin Z is molecularly designed and constructed via a combination of pressure-assisted vesicle adsorptionExpand
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An aquaporin-based vesicle-embedded polymeric membrane for low energy water filtration
Aquaporins (AQPs) are transmembrane water channel proteins that serve as nano-filters to selectively transport water molecules through plasma membranes in living cells at high speeds while blockingExpand
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MicroRNAs: biogenesis, function and applications.
MicroRNAs (miRNAs) belong to the group of non-coding, small RNAs (19 to 21 nucleotide-long oligonucleotides) that are endogenously produced from their own genes. miRNAs interfere with or affect theExpand
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Aquaporin gene expression and regulation in the ovine fetal lung
Fetal lung development is dependent upon secretion of liquid into the future airways which must be cleared at birth to establish air‐breathing. Aquaporins (AQP) 1, 3, 4 and 5 are membranous waterExpand
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Toxins in anti-nociception and anti-inflammation.
The use of toxins as novel molecular probes to study the structure-function relationship of ion-channels and receptors as well as potential therapeutics in the treatment of wide variety of diseasesExpand
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Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity?
Lowering of low-density lipoprotein cholesterol is well achieved by 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins). Statins inhibit the conversion of HMG-CoA toExpand
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