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The retinal tolerance to bevacizumab in co-application with a recombinant tissue plasminogen activator
Aim: To investigate the retinal toxicity of bevacizumab in co-application with a commercially available recombinant tissue plasminogen activator (rt-PA), and to facilitate a new therapeutic conceptExpand
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Comparative toxicity and proliferation testing of aflibercept, bevacizumab and ranibizumab on different ocular cells
Background/aims Vascular endothelial growth factor (VEGF) is a key factor in the pathogenesis of neovascular retinal diseases including age-related macular degeneration. VEGF inhibitors includingExpand
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Optical coherence tomography shows progressive local nerve fiber loss after disc hemorrhages in glaucoma patients
Background and aimThe aim of this work is to investigate whether optic disc hemorrhages (ODH) lead to significant loss of nerve fibers at the lesion site over time and whether such a loss isExpand
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The cross-linked biopolymer hyaluronic acid as an artificial vitreous substitute.
PURPOSE Biopolymers are promising substances in the development of a new vitreous substitute to overcome the drawbacks associated with current hydrophobic tamponade materials. METHODS DifferentExpand
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Electrophysiological effects of Brilliant Blue G in the model of the isolated perfused vertebrate retina
BackgroundTo facilitate epiretinal or inner limiting membrane peeling dyes like Indocyanine Green (ICG) as well as Trypan Blue (TB) were used so far. However, toxic effects on the retina wereExpand
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A modified scleral dissection technique with suprachoroidal drainage for canaloplasty
PurposeA modified canaloplasty technique is described that may facilitate the surgical procedure and potentially maximizes the intraocular pressure (IOP)-lowering effect by altering both theExpand
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Long-term results after artificial iris implantation in patients with aniridia
BackgroundThe custom-made, flexible artificial iris developed by HumanOptics and Koch can reconstruct the anterior segment of patients with aniridia. The aim of this study was to evaluate theExpand
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Micro-invasive 360-degree suture trabeculotomy after successful canaloplasty – one year results
PurposeThis study was conducted to analyse the intraocular pressure (IOP)-lowering and drug-sparing effect of micro-invasive 360-degree suture trabeculotomy after successfully performedExpand
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The effects of the intraocular dye brilliant blue G (BBG) mixed with varying concentrations of glucose on retinal function in an isolated perfused vertebrate retina
BackgroundDuring vitreoretinal surgery, vital dyes such as brilliant blue G (BBG) are used to visualize anatomical structures. By adding glucose to a concentration of 5%, many surgeons try to achieveExpand
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Evaluating retinal toxicity of a new heavy intraocular dye, using a model of perfused and isolated retinal cultures of bovine and human origin
BackgroundDyes such as brilliant blue (BBG) are used during vitreoretinal surgery to visualize anatomical structures. By adding deuterium oxide (D2O), surgeons have tried to create a dye mixtureExpand
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