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Intravascular photoacoustic imaging of human coronary atherosclerosis.
- K. Jansen, A. V. D. van der Steen, Heleen M. M. van Beusekom, J. W. Oosterhuis, G. van Soest
- Medicine, Materials Science
- Optics letters
- 1 March 2011
We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. The data was obtained from two fresh human coronary arteries ex vivo, showing different stages of disease.… Expand
Intravascular photoacoustic imaging: a new tool for vulnerable plaque identification.
The vulnerable atherosclerotic plaque is believed to be at the root of the majority of acute coronary events. Even though the exact origins of plaque vulnerability remain elusive, the thin-cap… Expand
Intravascular photoacoustic imaging of human coronary atherosclerosis
- K. Jansen, A. V. D. van der Steen, Geert Springeling, H. V. van Beusekom, J. W. Oosterhuis, G. van Soest
- Materials Science, Engineering
- 10 February 2011
We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. We specifically imaged lipid content, a key factor in vulnerable plaques that may lead to myocardial… Expand
Specific imaging of atherosclerotic plaque lipids with two-wavelength intravascular photoacoustics.
- M. Wu, K. Jansen, A. V. D. van der Steen, G. van Soest
- Biomedical optics express
- 1 September 2015
The lipid content in plaques is an important marker for identifying atherosclerotic lesions and disease states. Intravascular photoacoustic (IVPA) imaging can be used to visualize lipids in the… Expand
Impact of device geometry on the imaging characteristics of an intravascular photoacoustic catheter.
- M. Wu, K. Jansen, Geert Springeling, A. V. D. van der Steen, G. van Soest
- Materials Science, Medicine
- Applied optics
- 1 December 2014
A basic requirement for intravascular photoacoustic (IVPA) imaging catheters is that the delivery of light lies within the ultrasonic field of view. Size and manufacturing constraints favor probe… Expand
Photoacoustic imaging of human coronary atherosclerosis in two spectral bands☆
Spectroscopic intravascular photoacoustic imaging (sIVPA) has shown promise to detect and distinguish lipids in atherosclerotic plaques. sIVPA generally utilizes one of the two high absorption bands… Expand
Spectroscopic intravascular photoacoustic imaging of lipids in atherosclerosis
- K. Jansen, A. V. D. van der Steen, +7 authors G. van Soest
- Chemistry, Medicine
- Journal of biomedical optics
- 1 February 2014
Abstract. The natural history of atherosclerosis is marked by changes in the lipid biochemistry in the diseased arterial wall. As lesions become more vulnerable, different cholesterol species… Expand
Lipid detection in atherosclerotic human coronaries by spectroscopic intravascular photoacoustic imaging.
- K. Jansen, Min Wu, A. V. D. van der Steen, G. van Soest
- Materials Science, Medicine
- Optics express
- 9 September 2013
The presence of lipids in atherosclerotic coronary lesions is an important determinant of their potential to trigger acute coronary events. Spectroscopic intravascular photoacoustic imaging (sIVPA)… Expand
Imaging microvasculature with contrast-enhanced ultraharmonic ultrasound.
- D. Maresca, I. Skachkov, +4 authors A. V. D. van der Steen
- Ultrasound in medicine & biology
- 1 June 2014
Atherosclerotic plaque neovascularization was shown to be one of the strongest predictors of future cardiovascular events. Yet, the clinical tools for coronary wall microvasculature detection in vivo… Expand
Intravascular ultrasound chirp imaging
- D. Maresca, K. Jansen, +7 authors A. V. D. van der Steen
- Physics, Engineering
- IEEE International Ultrasonics Symposium
We demonstrate the feasibility of intravascular ultrasound chirp imaging. Chirp excitations were emitted with a 34 MHz single crystal intravascular transducer and compared to conventional Gaussian… Expand