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Blockade of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats.
The renin-angiotensin system may be involved in the maintenance of chronic left ventricular hypertrophy and blockade of the system may result in regression of the hypertrophic phenotype and improve survival in rats despite persistent pressure overload.
Minimally invasive diagnosis of renal artery stenosis by spiral computed tomography angiography.
CTA has the same accuracy for the diagnosis of RAS > or = 50% as arteriography, however, CTA is only minimally invasive, safe, and causes less discomfort to patients.
The Kissing Balloons Technique
- A. Chavan, M. Galanski, K. Jandeleit, M. Prokop, C. Schaefer
- MedicineActa radiologica
- 1 September 1993
This work presents a patient with hypertension and impaired function of the right kidney on account of a renal arterial bifurcation stenosis, and provides an elegant alternative to difficult surgery to save an endangered kidney.
Increased activity of the autonomic nervous system and increased sensitivity to angiotensin II infusion after therapy with recombinant human erythropoietin.
Epinephrine and particularly norepinephrine increased during rh-EPO therapy, with a peak at 6 weeks of treatment, and total peripheral resistance (TPR) calculated from mean arterial blood pressure as well.
MESENTERIC VASCULAR ANGIOTENSIN‐CONVERTING ENZYME IS INCREASED IN EXPERIMENTAL DIABETES MELLITUS
- K. Jandeleit, J. Rumble, B. Jackson, M. Cooper
- Medicine, BiologyClinical and experimental pharmacology…
- 1 May 1992
1. Diabetes mellitus was induced by streptozotocin in male Wistar rats, and angiotensin‐converting enzyme measured in plasma and mesenteric vessels 3 weeks later.
Genetic characterization of early renal changes in a novel mouse model of diabetic kidney disease.
Renal arterial stenoses: spiral CT angiography.
- M. Galanski, M. Prokop, A. Chavan, C. Schaefer, K. Jandeleit, J. Nischelsky
- 1 October 1993
Spiral CT angiography is a promising screening method for renal artery stenosis and axial-section and multiplanar reformatted images were superior to three-dimensional surface reconstructions and maximum-intensity projections.
Diabetes-Associated Mesenteric Vascular Hypertrophy Is Attenuated by Angiotensin-Converting Enzyme Inhibition
- M. Cooper, J. Rumble, R. Komers, Du He-Cheng, K. Jandeleit, Chou Sheung-To
- Medicine, BiologyDiabetes
- 1 October 1994
ACE inhibition may have a specific role in preventing diabetes-associated vascular hypertrophy, an important process in the genesis of micro- and macrovascular diabetic complications.
Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure.
- J. Kindler, K. Eckardt, H. Sieberth
- Medicine, BiologyNephrology, dialysis, transplantation : official…
The results indicate that, in accordance with animal data, the elimination of rHuEpo occurs mainly through non-renal mechanisms.
Intrarenal renin-angiotensin system in renal physiology and pathophysiology.
It has now been demonstrated by several techniques that all components of the renin-angiotensin system reside within the kidney. It is likely that angiotensin II is formed within interstitial renal…