• Publications
  • Influence
Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization.
In this study we demonstrate that planar cell polarity signaling regulates morphogenesis in Xenopus embryos in part through the assembly of the fibronectin (FN) matrix. We outline a regulatoryExpand
  • 169
  • 16
Tissue engineering by self-assembly and bio-printing of living cells.
Biofabrication of living structures with desired topology and functionality requires the interdisciplinary effort of practitioners of the physical, life and engineering sciences. Such efforts areExpand
  • 438
  • 9
Engineering biological structures of prescribed shape using self-assembling multicellular systems.
Self-assembly is a fundamental process that drives structural organization in both inanimate and living systems. It is in the course of self-assembly of cells and tissues in early development thatExpand
  • 305
  • 6
The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors.
Impairment of tissue cohesion and the reorganization of the extracellular matrix are crucial events during the progression toward invasive cell phenotype. We studied the in vitro invasion patterns ofExpand
  • 94
  • 6
Tissue engineering by self-assembly of cells printed into topologically defined structures.
Understanding the principles of biological self-assembly is indispensable for developing efficient strategies to build living tissues and organs. We exploit the self-organizing capacity of cells andExpand
  • 291
  • 5
Toward engineering functional organ modules by additive manufacturing.
Tissue engineering is emerging as a possible alternative to methods aimed at alleviating the growing demand for replacement tissues and organs. A major pillar of most tissue engineering approaches isExpand
  • 230
  • 5
Designer ‘blueprint’ for vascular trees: morphology evolution of vascular tissue constructs
Organ printing is a variant of the biomedical application of rapid prototyping technology or layer-by-layer additive biofabrication of 3D tissue and organ constructs using self-assembled tissueExpand
  • 28
  • 4
Magnetic tweezers for intracellular applications
We have designed and constructed a versatile magnetic tweezer primarily for intracellular investigations. The micromanipulator uses only two coils to simultaneously magnetize to saturationExpand
  • 107
  • 2
Role of physical mechanisms in biological self-organization.
Organs form during morphogenesis, the process that gives rise to specialized biological structures of specific shape and function in early embryonic development. Morphogenesis is under strict geneticExpand
  • 60
  • 2
Relating cell and tissue mechanics: Implications and applications
The Differential Adhesion Hypothesis (DAH) posits that differences in adhesion provide the driving force for morphogenetic processes. A manifestation of differential adhesion is tissue liquidity andExpand
  • 58
  • 2