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Expression of the growth arrest-specific gene 6 (GAS6) in leukemia and lymphoma cell lines.
The initial identification of GAS6 as a protein expressed in response to growth arrest suggested that it might function as a negative regulator of cell proliferation. Since the transforming activityExpand
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Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair
The appearance of hair is one of the main evolutionary innovations in the amniote lineage leading to mammals. The main components of mammalian hair are cysteine-rich type I and type II keratins, alsoExpand
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Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.
KRT75 (formerly known as K6hf) is one of the isoforms of the keratin 6 (KRT6) family located within the type II cytokeratin gene cluster on chromosome 12 of humans and chromosome 15 of mice. KRT75 isExpand
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The insertion sequences of Anabaena sp. strain PCC 7120 and their effects on its open reading frames.
Anabaena sp. strain PCC 7120, widely studied, has 145 annotated transposase genes that are part of transposable elements called insertion sequences (ISs). To determine the entirety of the ISs, weExpand
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Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails.
Degradation of nuclear DNA is a hallmark of programmed cell death. Epidermal keratinocytes die in the course of cornification to function as the dead building blocks of the cornified layer of theExpand
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Trichohyalin-like proteins have evolutionarily conserved roles in the morphogenesis of skin appendages.
S100 fused-type proteins (SFTPs) such as filaggrin, trichohyalin, and cornulin are differentially expressed in cornifying keratinocytes of the epidermis and various skin appendages. To determineExpand
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Terminal differentiation of nail matrix keratinocytes involves up-regulation of DNase1L2 but is independent of caspase-14 expression.
Terminal differentiation of keratinocytes in the epidermis and in epidermal appendages results in specialized forms of cell death. Keratinocytes of the nail matrix differentiate into nailExpand
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The anatomy and development of the claws of Xenopus laevis (Lissamphibia: Anura) reveal alternate pathways of structural evolution in the integument of tetrapods
Digital end organs composed of hard, modified epidermis, generally referred to as claws, are present in mammals and reptiles as well as in several non‐amniote taxa such as clawed salamanders andExpand
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Was wissen Psychiater über die Kinder ihrer Patienten
Anliegen: Untersuchung der Aufmerksamkeit von Psychiatern gegenuber Kindern ihrer Patienten sowie ihrer Einstellung zur Jugendhilfe und Pravention. Methode: Fragebogenbefragung an 7 Kliniken furExpand
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Sub-Cellular Element Analysis of a Cyanobacterium (Nostoc sp.) in Symbiosis with Gunnera manicata by ESI and EELS
: Element analysis using electron spectroscopic imaging (ESI) and electron energy loss spectroscopy (EELS) was performed in a symbiotic Nostoc sp. strain found in the upper stem tissue of GunneraExpand
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