• Publications
  • Influence
A new artificial cyclase for polyprenoids: enantioselective total synthesis of (-)-chromazonarol, (+)-8-epi-puupehedione, and (-)-11'-deoxytaondiol methyl ether.
This paper describes a new artificial cyclase, optically pure 3-o-fluorobenzyloxy-2-hydroxy-2'-(p-methoxybemzyl)-1,1'-binaphthyl.SnCl4, which is effective for the enantioselective cyclization ofExpand
  • 118
  • 2
Widely useful DMAP-catalyzed esterification under auxiliary base- and solvent-free conditions.
With regard to atom economy and E-factor, catalytic condensation of carboxylic acids with equimolar amounts of alcohols is the most desirable. Although several highly active dehydration catalystsExpand
  • 147
  • 2
Hypervalent iodine-mediated oxidation of alcohols.
Over the past two decades there has been a dramatic increse in the use of hypervalent iodine compounds in synthetic organic chemistry due to their mild and selective oxidizing properties. HypervalentExpand
  • 346
  • 1
3,4,5-Trifluorobenzeneboronic Acid as an Extremely Active Amidation Catalyst.
  • 278
  • 1
Highly efficient alkylation to ketones and aldimines with Grignard reagents catalyzed by zinc(II) chloride.
A highly efficient alkylation to ketones and aldimines with Grignard reagents in the presence of catalytic trialkylzinc(II) ate complexes derived from ZnCl2 (10 mol %) in situ was developed. ThisExpand
  • 137
  • 1
Cyanuric chloride as a mild and active Beckmann rearrangement catalyst.
The first general organocatalytic Beckmann rearrangement of ketoximes into amides has been realized by the catalytic use of cyanuric chloride. Furthermore, acids such as HCl and ZnCl2 are effectiveExpand
  • 147
  • 1
Design of Brønsted Acid-Assisted Chiral Lewis Acid (BLA) Catalysts for Highly Enantioselective Diels−Alder Reactions
Bronsted acid-assisted chiral Lewis acid (BLA) was highly effective as a chiral catalyst for the enantioselective Diels−Alder reaction of both α-substituted and α-unsubstituted α,β-enals with variousExpand
  • 108
  • 1
Highly alkyl-selective addition to ketones with magnesium ate complexes derived from Grignard reagents.
A highly efficient alkyl-selective addition to ketones with magnesium ate complexes derived from Grignard reagents and alkyllithiums is described. The nucleophilicity of R in R3MgLi is remarkablyExpand
  • 57
  • 1