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Usnic acid.
Since its first isolation in 1844, usnic acid [2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bH)-dibenzo-furandione] has become the most extensively studied lichen metabolite and one of the fewExpand
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Antimycobacterial activity of lichen metabolites in vitro.
Several compounds, whose structures represent the most common chemical classes of lichen metabolites, were screened for in vitro activity against Mycobacterium aurum, a non-pathogenic organism with aExpand
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Mechanistic evaluation of new plant-derived compounds that inhibit HIV-1 reverse transcriptase.
Swertifrancheside [1], a new flavonone-xanthone glucoside isolated from Swertia franchetiana, 1 beta-hydroxyaleuritolic acid 3-p-hydroxybenzoate [2], a triterpene isolated from the roots of MaprouneaExpand
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Cellular mechanisms of the anticancer effects of the lichen compound usnic acid.
The lichen compound usnic acid is used for its antimicrobial activities in cosmetic products and is also a component of slimming agents. Its effect against cancer cells was first noted over 30 yearsExpand
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Natural Products: Anti‐proliferative Effects of Lichen‐derived Inhibitors of 5‐Lipoxygenase on Malignant Cell‐lines and Mitogen‐stimulated Lymphocytes
Several lichen species have been used traditionally as medicinal plants. It has previously been shown that two low‐molecular‐weight lichen metabolites, lobaric acid isolated from Stereocaulon alpinumExpand
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Polysaccharides from lichens: structural characteristics and biological activity.
Lichens have been used for medicinal purposes throughout the ages, and beneficial claims have to some extent been correlated with their polysaccharide content. Of 13,500 lichen species growingExpand
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In vitro evaluation of the antimicrobial activity of lichen metabolites as potential preservatives.
Antimicrobial screening of several lichen species and subsequent isolation and structure elucidation of active compounds revealed that the hydrolysis products of certain lichen metabolites, i.e.,Expand
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Effects of tenuiorin and methyl orsellinate from the lichen Peltigera leucophlebia on 5-/15-lipoxygenases and proliferation of malignant cell lines in vitro.
The orcinol derivatives tenuiorin (1) and methyl orsellinate (2) were identified as active components of an extract from the lichen Peltigera leucophlebia (Nyl.) Gyeln. showing in vitro inhibitoryExpand
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Anti-proliferative lichen compounds with inhibitory activity on 12(S)-HETE production in human platelets.
Several lichen compounds, i.e. lobaric acid (1), a beta-orcinol depsidone from Stereocaulon alpinum L., (+)-protolichesterinic acid (2), an aliphatic alpha-methylene-gamma-lactone from CetrariaExpand
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Solubilization of poorly soluble lichen metabolites for biological testing on cell lines.
The depside atranorin and depsidone fumarprotocetraric acid, isolated from the lichens Stereocaulon alpinum and Cetraria islandica, respectively, were chosen as prototypes for poorly soluble naturalExpand
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