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Iridoid Glucosides with Free Radical Scavenging Properties from Fagraea blumei
Four new iridoid glucosides 1–4, named blumeosides A–D, were isolated from the methanolic stem-bark extract of Fagraea blumei G. DON. (Loganiaceae). They were accompanied by the benzyl-alcoholExpand
7. Bioactivity in plants: the link between phytochemistry and medicine
Abstract The development of medicinal plant research over the last 30 years is reviewed with reference to the search for new active principles. Difficulties inherent to activity guided isolation andExpand
The Potential of African Plants as a Source of Drugs
An outline is presented here covering the results obtained by the Institute of Pharmacognosy and Phytochemistry of the University of Lausanne during 15 years' work on African plants, covering all aspects from the selection of plant material to the isolation of pure natural products. Expand
Evaluation of quadrupole time-of-flight tandem mass spectrometry and ion-trap multiple-stage mass spectrometry for the differentiation of C-glycosidic flavonoid isomers.
The collision-induced dissociation MS-MS spectra of ubiquitous C-glycosidic flavonoids have been systematically studied using hybrid quadrupole time-of-flight and ion-trap mass analysers under various CID energy conditions. Expand
Developments in the application of counter-current chromatography to plant analysis.
Counter-current chromatography is a very versatile separation technique which does not require a solid stationary phase and is complementary to other chromatographic methods and is compatible with gradient systems. Expand
A bioautographic agar overlay method for the detection of antifungal compounds from higher plants
A simple bioautographic agar overlay assay using Candida albicans as the indicator organism for the detection and activity-guided fractionation of antifungal compounds by thin layer chromatographyExpand
Inhibition of 5 alpha-reductase and aromatase by the ellagitannins oenothein A and oenothein B from Epilobium species.
Quantitation of oenothein B in 10 different species of Epilobium has shown that amounts of up to 14% in the crude plant extracts are possible, and activity-guided fractionation has led to the identification of two macrocyclic ellagitannins, oanothein A and oenethein B, as the main constituents responsible for the inhibition of the two enzymes. Expand
Traditional medicine in north Côte-d'Ivoire: screening of 50 medicinal plants for antibacterial activity.
Evidence is provided that some of the studied plants might indeed be potential sources of new antibacterial agents, also against some antibiotic-resistant strains. Expand
Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors.
In order to discover new acetylcholinesterase (AChE) inhibitors, different plant extracts were screened by a previously established TLC bioautographic method and four xanthones, bellidin, bellidsifolin, and bellidifolin 8-O-beta-glucopyranoside, were found to be responsible for the anti-A ChE activity effects. Expand