• Publications
  • Influence
Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.
We have cloned two distinct mouse heat shock transcription factor genes, mHSF1 and mHSF2. The mHSF1 and mHSF2 open reading frames are similar in size, containing 503 and 517 amino acids,Expand
  • 268
  • 15
The morning salivary cortisol response in burnout.
OBJECTIVES The aim of the present study was to examine the free salivary cortisol response to awakening in men and women reporting low, moderate, and high levels of burnout. METHODS Twenty-twoExpand
  • 160
  • 15
E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription
The E2F family of transcription factors are essential for the regulation of genes required for appropriate progression through the cell cycle. Five members of the E2F family have been previouslyExpand
  • 202
  • 12
Phosphorylation‐dependent and ‐independent functions of p130 cooperate to evoke a sustained G1 block
The retinoblastoma (pRb)‐related p130 pocket protein is a regulator of cell growth and differentiation, and a candidate tumour suppressor. Both pRb and p130 operate through interactions with cellularExpand
  • 91
  • 12
Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression.
The E2F family of transcription factors regulate genes, whose products are essential for progression through the mammalian cell cycle. The transcriptional activity of the E2Fs is inhibited throughExpand
  • 280
  • 10
Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma.
The retinoblastoma gene family consists of the tumor suppressor protein pRB and its two relatives p107 and p130. These proteins have been implicated in the regulation of cell cycle progression, inExpand
  • 126
  • 3
Sweetness and texture perceptions in structured gelatin gels with embedded sugar rich domains
Layered and homogeneous gelatin gels with controlled theological properties were compared for their sensory characteristics, specifically sweetness, hardness, breakdown behaviour and frothing. AllExpand
  • 49
  • 3
Distinct Phosphorylation Events Regulate p130- and p107-mediated Repression of E2F-4*
The “pocket proteins” pRb (retinoblastoma tumor suppressor protein), p107, and p130 regulate cell proliferation via phosphorylation-sensitive interactions with E2F transcription factors and otherExpand
  • 61
  • 2
Factors intrinsic to the neuron can induce and maintain its ability to promote axonal outgrowth: a role for BCL2?
The adult CNS provides a poor environment for axonal growth and regeneration. The question of to what extent the loss of axonal growth occurring as the brain matures is dependent on factors intrinsicExpand
  • 50
  • 1
Early innervation of the metanephric kidney.
During kidney differentiation, the nephrogenic mesenchyme converts into renal tubules and the ureter bud branches to form the collecting system. Here we show that in the early undifferentiated kidneyExpand
  • 42
  • 1