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Acne and Propionibacterium acnes.
The involvement of microorganisms in the development of acne has a long and checkered history. Just over 100 years ago, Propionibacterium acnes (then known as Bacillus acnes) was isolated from acneExpand
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Is the GehD Lipase from Staphylococcus epidermidis a Collagen Binding Adhesin?*
The opportunistic human pathogenStaphylococcus epidermidis is the major cause of nosocomial biomaterial infections. S. epidermidis has the ability to attach to indwelling materials coated withExpand
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Comparison of 16-Androstene steroid concentrations in sterile apocrine sweat and axillary secretions: Interconversions of 16-Androstenes by the axillary microflora—a mechanism for axillary odour
The concentrations of five 16-androstene steroids were determined, by a GC-MS method, in freshly-produced apocrine sweat (adrenaline-induced), in 8 men and 2 women. The ranges of concentrationsExpand
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Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus
Background Human growth factors are potential therapeutic agents for various inflammatory disorders affecting the gastrointestinal tract. However, they are unstable when administered orally andExpand
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In vitro modulation of human keratinocyte pro- and anti-inflammatory cytokine production by the capsule of Malassezia species.
Malassezia spp. are commensal, cutaneous fungi that are implicated in seborrhoeic dermatitis. We hypothesize that the lipid-rich capsule of Malassezia spp. masks the organism from host detection, andExpand
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Erythromycin resistant propionibacteria in antibiotic treated acne patients: association with therapeutic failure
Erythromycin resistant (EmR propionibacteria were isolated from the skin surface of 51% of patients treated with oral erythromycin and 42% of patients treated with topical clindamycin compared withExpand
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Proinflammatory cytokine production by human keratinocytes stimulated with Propionibacterium acnes and P. acnes GroEL
Background  Keratinocytes form the first line of defence in the skin and alert the host to danger by the production of a number of cytokines and chemokines. However, the interaction of commensalExpand
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Interaction of Propionibacterium acnes with skin lipids in vitro.
Propionibacterium acnes is the predominant microbial resident within the pilosebaceous follicles of sebum-rich areas of human skin. This study investigated the effects of known hydrophobic componentsExpand
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The hyaluronate lyase of Staphylococcus aureus - a virulence factor?
The hyaluronate lyase (HL) gene of Staphylococcus aureus 8325-4 (hysA) was inactivated in vitro with the insertion of the erythromycin determinant, ermC, from plasmid pE194. The hysA : : ermCExpand
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Review: the human cutaneous microflora and factors controlling colonisation
The human skin is an unusual habitat for microorganisms in that it is open to contamination from the environment and yet is largely unsuitable for microbial colonisation, unlike mucosal surfaces. TheExpand
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