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Plasticity of hyperpolarization‐activated and cyclic nucleotid‐gated cation channel subunit 2 expression in the spinal dorsal horn in inflammatory pain
A great deal of experimental evidence has already been accumulated that hyperpolarization‐activated and cyclic nucleotide‐gated cation channels (HCN) expressed by peripheral nerve fibers contributeExpand
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Neuronal and glial localization of the cannabinoid‐1 receptor in the superficial spinal dorsal horn of the rodent spinal cord
A long line of experimental evidence indicates that endogenous cannabinoid mechanisms play important roles in nociceptive information processing in various areas of the nervous system including theExpand
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Hyperpolarization‐activated and cyclic nucleotide‐gated cation channel subunit 2 ion channels modulate synaptic transmission from nociceptive primary afferents containing substance P to secondary
We have previously demonstrated that hyperpolarization‐activated and cyclic nucleotide‐gated cation channel subunit 2 (HCN2) is expressed by terminals of peptidergic nociceptive primary afferents inExpand
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Type X collagen in human enamel development: a possible role in mineralization
Although type X collagen is one of the key molecules in endochondral ossification, no data are available on whether it is present in dental structures when mineralization is proceeding. We thereforeExpand
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A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice.
Aggrecan, the high buoyant density cartilage proteoglycan (PG), has been shown to induce progressive polyarthritis and ankylosing spondylitis in genetically susceptible BALB/c mice. To furtherExpand
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Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)‐induced arthritis
The central role of CD4+ T cells and the balance between T helper (Th) subpopulations in the pathogenesis of autoimmune diseases have been extensively studied. Proteoglycan (aggrecan)‐inducedExpand
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Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan‐induced arthritis
Immunization of BALB/c mice with human fetal cartilage proteoglycan (PG) produces progressive polyarthritis, and T ceils play key roles in the development of the disease. To gain an understanding ofExpand
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Okadaic acid-induced inhibition of protein phosphatase 2A enhances chondrogenesis in chicken limb bud micromass cell cultures
The role of major cellular serine/threonine-specific protein phosphatases, protein phosphatase 1 and 2A, was investigated during chicken cartilage differentiation under in vitro conditions. ActivityExpand
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Effect of pregnancy on proteoglycan‐induced progressive polyarthritis in BALB/c mice: remission of disease activity
Proteoglycan‐induced arthritis is a murine autoimmune model displaying many similarities to human rheumatoid arthritis and ankylosing spondylitis, as has been documented by clinical, immunologicalExpand
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Differential distribution of diacylglycerol lipase‐alpha and N‐acylphosphatidylethanolamine‐specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats
It is generally accepted that the endocannabinoid system plays important roles in spinal pain processing. Although it is documented that cannabinoid‐1 receptors are strongly expressed in theExpand
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