Evolution and genetic diversity of Theileria.
- T. Sivakumar, K. Hayashida, C. Sugimoto, N. Yokoyama
- BiologyInfection, Genetics and Evolution
- 1 October 2014
Whole-Genome Sequencing of Theileria parva Strains Provides Insight into Parasite Migration and Diversification in the African Continent
- K. Hayashida, T. Abe, C. Sugimoto
- BiologyDNA Research
- 12 February 2013
The phylogeny of T. parva strains is elucidated based on genome-wide SNPs analysis with prediction of possible past recombination events, providing insight into the migration, diversification, and evolution of this parasite species in the African continent.
Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
- Jesca Nakayima, R. Nakao, C. Sugimoto
- BiologyParasite
- 1 July 2013
This study suggests existence of distinct genetic diversity between T. vivax genotypes from West Africa and Zambia as per their geographical origins.
Comparative Genome Analysis of Three Eukaryotic Parasites with Differing Abilities To Transform Leukocytes Reveals Key Mediators of Theileria-Induced Leukocyte Transformation
- K. Hayashida, Yuichiro Hara, C. Sugimoto
- BiologymBio
- 4 September 2012
The genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle, was sequenced and compared it to the published sequences representative of two malignant, transforming species, T. parva and T. annulata.
MDM2 regulates a novel form of incomplete neoplastic transformation of Theileria parva infected lymphocytes.
- K. Hayashida, K. Kajino, C. Sugimoto
- BiologyExperimental and molecular pathology (Print)
- 1 February 2013
Genetic diversity of benign Theileria parasites of cattle in the Okinawa Prefecture.
- S. Zakimi, Jung-Yeon Kim, M. Oshiro, K. Hayashida, K. Fujisaki, C. Sugimoto
- Biology, MedicineJournal of Veterinary Medical Science
- 1 December 2006
Benign Theileria parasites of cattle distributed in the Okinawa prefecture were characterized by allele-specific polymerase chain reaction (PCR) and DNA sequence analysis of the major piroplasm…
The PCR detection and phylogenetic characterization of Babesia microti in questing ticks in Mongolia.
- Bumduuren Tuvshintulga, T. Sivakumar, N. Yokoyama
- BiologyParasitology international
- 1 December 2015
Amoebal Endosymbiont Neochlamydia Genome Sequence Illuminates the Bacterial Role in the Defense of the Host Amoebae against Legionella pneumophila
- Kasumi Ishida, T. Sekizuka, Hiroyuki Yamaguchi
- BiologyPLoS ONE
- 18 April 2014
The draft genome sequence of Neochlamydia S13 revealed several defects in essential metabolic pathways, as well as unique molecules with leucine-rich repeats (LRRs) and ankyrin domains, responsible for protein-protein interaction, which illuminate the role of the endosymbiont in the defense of the host amoebae against Legionella infection.
Direct Blood Dry LAMP: A Rapid, Stable, and Easy Diagnostic Tool for Human African Trypanosomiasis
- K. Hayashida, K. Kajino, L. Hachaambwa, B. Namangala, C. Sugimoto
- BiologyPLoS Neglected Tropical Diseases
- 1 March 2015
This study made several substantial modifications to the technique to carry out on-site diagnosis of Human African Trypanosomiasis in remote areas using LAMP, which could greatly impact on the application of diagnosis not only for HAT but also for other tropical diseases.
Direct detection of falciparum and non-falciparum malaria DNA from a drop of blood with high sensitivity by the dried-LAMP system
- K. Hayashida, K. Kajino, C. Sugimoto
- MedicineParasites & Vectors
- 13 January 2017
These malaria CZC-LAMPs provide new means for rapid, sensitive and reliable point-of-care diagnosis for low-density malaria infections, and are expected to help update current knowledge of malaria epidemiology, and can contribute to the elimination of malaria from endemic areas.
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