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Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum.
A new aquaporin (AQP10) was identified in human small intestine. This gene encoded a 264-amino-acid protein with high sequence identity with AQP3 (53%), 9 (52%), and 7 (43%). These AQPs constituteExpand
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Zyxin, a Regulator of Actin Filament Assembly, Targets the Mitotic Apparatus by Interacting with H-Warts/Lats1 Tumor Suppressor
The mitotic apparatus plays a pivotal role in dividing cells to ensure each daughter cell receives a full set of chromosomes and complement of cytoplasm during mitosis. A human homologue of theExpand
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Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells.
In the present study, we investigated methylation status of the CpG islands of some major tumor suppressor genes both in human hepatocellular carcinoma and liver cancer cell lines and examinedExpand
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Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice.
Although inorganic arsenate (iAs(V)) or arsenite (iAs(III)) is clearly a human carcinogen, it has been difficult to produce tumors in rodents. In the present study, we orally administered iAs(V) toExpand
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Recurrence pattern of squamous cell carcinoma of the thoracic esophagus after extended radical esophagectomy with three-field lymphadenectomy.
BACKGROUND Extended radical esophagectomy with three-field lymphadenectomy for patients with thoracic esophageal cancer has been shown to be effective. But even if this operation is performed, someExpand
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Expression and localization of aquaporins in rat gastrointestinal tract.
A family of water-selective channels, aquaporins (AQP), has been demonstrated in various organs and tissues. However, the localization and expression of the AQP family members in the gastrointestinalExpand
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Clinical significance of lymph node micrometastasis in gallbladder carcinoma.
BACKGROUND This retrospective study was intended to define the clinical significance of lymph node micrometastasis in gallbladder carcinoma. METHODS A total of 1136 regional lymph nodes taken fromExpand
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The complete removal of cohesin from chromosome arms depends on separase
Cohesin needs to be removed from chromosomes to allow sister chromatid separation in mitosis. In vertebrates, two pathways contribute to this process. The prophase pathway, which requiresExpand
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High risk of gallbladder carcinoma in elderly patients with segmental adenomyomatosis of the gallbladder.
The clinical significance of adenomyomatosis of the gallbladder remains unclear. This study aimed to clarify the relationship between segmental adenomyomatosis and gallbladder carcinoma, and toExpand
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Impact of ductal resection margin status on long‐term survival in patients undergoing resection for extrahepatic cholangiocarcinoma
The current study was performed to clarify whether the presence of residual carcinoma in situ at ductal resection margins differs prognostically from residual invasive ductal lesions in patientsExpand
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