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Involvement of nipple and areola in early breast cancer
TLDR
Analysis of nipple‐areolar involvement with consideration of the different variables indicates that it occurred in association with tumor size, tumor‐areola distance, and histologic type. Expand
Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite.
TLDR
It was revealed that the quantity of doxorubicin hydrochloride released from HAP containing the drug (DOX) was increased by raising the temperature, indicating that the antitumor effect of the DOX-HAP complex + hyperthermia system was greater than that of either theDOX- HAP complex or hyperThermia system alone. Expand
Usefulness of Lens culinaris agglutinin A-reactive fraction of alpha-fetoprotein (AFP-L3) as a marker of distant metastasis from hepatocellular carcinoma.
TLDR
The results suggest that AFP-L3 is a useful indicator of distant metastasis and a poor prognosis for HCC. Expand
Implantation treatment method of slow release anticancer doxorubicin containing hydroxyapatite (DOX-HAP) complex. A basic study of a new treatment for hepatic cancer.
TLDR
The experimental study on slow releasing anticancer drug implantation treatment as a new therapy for hepatocellular carcinoma found that VX2 liver tumour growth on white rabbit was inhibited by implantation of DOX-HAP, without acute toxicity. Expand
[Preservation of the nipple and areola for breast cancer--histopathological study on cancerous involvement of the nipple and areola].
TLDR
Analysis of nipple-areolar involvement with consideration of the different variables indicates that it occurred in association with tumor size, tumor-areola distance and histological type. Expand
Percutaneous injection of a low-concentration alkaline solution targeting hepatocellular carcinoma.
TLDR
PLAIT has promise as a new form of local therapy for HCC, and Histopathological observation of normal rat livers after injection of 2 N NaOH at a volume of 0.05 ml showed that the tissue necrosis spread radially from the site immediately after injection by PLAIT, but necroses were not found in other organs. Expand
Role of thoracotomy in pulmonary metastases from gestational choriocarcinoma.
TLDR
Thoracotomy is used for therapeutic purposes only when the pulmonary lesion is the only remaining source of increased HCG excretion and much attention must be paid to tertiary hematogeneous metastases caused by resection of pulmonary foci that are unresponsive to chemotherapy. Expand
Antitumor effects of Doxorubicin hydrochloride (dox) and buthionine sulfoximine (bso)-hydroxyapatite (hap) complex on transplanted tumors in-vivo.
TLDR
It is concluded that the antitumor effect of the DOX and BSO-HAP complex was increased through depletion of the intracellular radical scavenger glutathione (GSH) by released BSO and subsequently free radicals produced by released DOX. Expand
Viability of canine lung after temporary ischemia under cooling. An electron microscopy study.
TLDR
The observations clearly show the importance of changes in the endothelium as a cause of gross lung edema, hence such should be considered when evaluating the viability of a donor lung. Expand
Hydroxyapatite beads containing Doxorubicin hydrochloride (dox) and buthionine sulfoximine (bso) - a new anticancer drug design for local treatment with multiple-drugs.
TLDR
This complex has potential as a new drug delivery system (DDS) in cancer chemotherapy and it is possible that intracellular glutathione could be depleted first by the rapidly released BSO and that DNA strand breaks could then be intensified by the slowly released DOX. Expand
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