Share This Author
Tooth surface-pellicle lipids and their role in the protection of dental enamel against lactic-acid diffusion in man.
Effect of aspirin on conformation and dynamics of membrane proteins in platelets and erythrocytes.
Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency.
Anticancer Activity of Natural Compounds from Plant and Marine Environment
The chemical structure of the molecules of these substances, their properties, mechanisms of action, their structure–activity relationships, along with their anticancer properties and their potential as chemotherapeutic drugs are discussed in this paper.
The effect of the nitroxide pirolin on oxidative stress induced by doxorubicin and taxanes in the rat brain.
- S. Tabaczar, J. Czepas, A. Koceva-Chyła, E. Kilańczyk, J. Piasecka-Zelga, K. Gwoździński
- Biology, ChemistryJournal of physiology and pharmacology : an…
- 1 April 2017
PL, in combination with anticancer drugs, partially protected the rat brain against the toxic effects of DOX and taxanes, highlighting its potential application in protecting the brain against DOX-, DTX- and PTX-evoked OS.
ANTIOXIDANT CAPACITY AND PHYSICAL EXERCISE
The characteristics of components of plasma antioxidant capacity, the mechanisms of free radicals production and their role in human body are presented and the currently used methods of detecting changes in total antioxidant capacity and its individual elements in response to single bout of exercise and regular training are discussed.
A spin-label study of the effect of gamma radiation on erythrocyte membrane. Influence of lipid peroxidation on membrane structure.
- E. Grzelińska, G. Bartosz, K. Gwoździński, W. Leyko
- Biology, PhysicsInternational journal of radiation biology and…
Membrane proteins underwent radiation-induced conformational transitions revealed by maleimide spin label which could be also connected with lipid peroxidation, which corresponded to dose dependence of malondialdehyde formation in the membranes.
Gastric mucin hydrophobicity: effects of associated and covalently bound lipids, proteolysis, and reduction.
- K. Gwoździński, A. Slomiany, H. Nishikawa, K. Okazaki, B. Slomiany
- Biology, ChemistryBiochemistry international
- 1 November 1988
Results indicate that lipids contribute to the hydrophobic character of gastric mucin and that hydrophilic binding sites reside on the nonglycosylated regions of the glycoprotein polymer buried within its core.
Nitroxides as Antioxidants and Anticancer Drugs
- M. Lewandowski, K. Gwoździński
- Chemistry, BiologyInternational journal of molecular sciences
- 1 November 2017
New natural spin-labelled derivatives of nitroxides, including camptothecin, rotenone, combretastatin, podophyllotoxin and others are focused on in this article.
Reactive Oxygen Species and Their Involvement in Red Blood Cell Damage in Chronic Kidney Disease
- K. Gwoździński, A. Pieniazek, L. Gwozdzinski
- BiologyOxidative medicine and cellular longevity
- 25 February 2021
A reduced antioxidant capacity is observed, associated with a decrease in the activity of SOD, GPx, PRDX2, and low molecular weight antioxidants, and their contribution to cardiovascular disease are discussed.