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- Publications
- Influence
Retinopathy induced in mice by targeted disruption of the rhodopsin gene
- M. Humphries, D. Rancourt, +11 authors P. Humphries
- Biology, Medicine
- Nature Genetics
- 1 February 1997
Retinitis pigmentosa (RP) represents the most common mendelian degenerative retinopathy of man, involving death of rod photoreceptors, cone cell degeneration, retinal vessel attenuation and… Expand
Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal
- K. Gulya, K. Grant, P. Valverius, P. Hoffman, B. Tabakoff
- Chemistry, Medicine
- Brain Research
- 26 April 1991
Previous work, using membrane receptor binding techniques, demonstrated an increase in hippocampal MK-801 binding sites in mice after chronic ethanol ingestion. The current studies, using… Expand
Cholinotoxic Effects of Aluminum in Rat Brain
- K. Gulya, Z. Rakonczay, Péter Kása
- Biology, Medicine
- Journal of neurochemistry
- 1 March 1990
Abstract: The in vivo and in vitro effects of A1 on the cholinergic system of rat brain were studied. The amount of A1 accumulated after the chronic, intraperitoneal administration of aluminum… Expand
Central effects of the potent and highly selective mu opioid antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) in mice.
- K. Gulya, M. Kriván, N. Nyolczas, Z. Sarnyai, G. Kovács
- Chemistry, Medicine
- European journal of pharmacology
- 10 June 1988
The ability of the selective cyclic mu-opioid receptor antagonist, D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP), to inhibit the acute and chronic effects of morphine in vivo was studied in mice.… Expand
Chronic ethanol ingestion decreases vasopressin mRNA in hypothalamic and extrahypothalamic nuclei of mouse brain
- K. Gulya, J. Dave, P. Hoffman
- Biology, Medicine
- Brain Research
- 23 August 1991
Endogenous arginine vasopressin was previously shown to modulate the rate of loss of functional (CNS) tolerance to ethanol, suggesting that chronic ethanol ingestion might alter vasopressin synthesis… Expand
Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-l-deprenyl using whole hemisphere autoradiography
- B. Gulyás, E. Pavlova, Péter Kása, K. Gulya, C. Halldin
- Chemistry, Medicine
- Neurochemistry International
- 31 January 2011
In the human brain the monoaminooxidase-B enzyme or MAO-B is highly abundant in astrocytes. As astrocyte activity and, consequently, the activity of the MAO-B enzyme, is up-regulated in… Expand
Central effects of the potent and highly selective μ opioid antagonist (CTOP) in mice
- K. Gulya, M. Kriván, N. Nyolczas, Z. Sarnyai, G. Kovács
- Chemistry
- 10 June 1988
Abstract The ability of the selective cyclic μ-opioid receptor antagonist, (CTOP), to inhibit the acute and chronic effects of morphine in vivo was studied in mice. Intracerebroventricular (i.c.v.)… Expand
A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high…
- B. Gulyás, Boglárka Makkai, Péter Kása, K. Gulya, C. Halldin
- Biology, Medicine
- Neurochemistry International
- 31 January 2009
The binding of two radiolabelled analogues (N-(5-[125I]Iodo-2-phenoxyphenyl)-N-(2,5-dimethoxybenzyl)acetamide ([125I]desfluoro-DAA1106) and… Expand
The cholinergic system in Alzheimer's disease
- Péter Kása, Z. Rakonczay, K. Gulya
- Psychology, Medicine
- Progress in Neurobiology
- 1 August 1997
The past decade has witnessed an enormous increase in our knowledge of the variety and complexity of neuropathological and neurochemical changes in Alzheimer's disease. Although the disease is… Expand
Prodynorphin and vasopressin mRNA levels are differentially affected by chronic ethanol ingestion in the mouse.
- K. Gulya, A. Orpana, J. Sikela, P. Hoffman
- Biology, Medicine
- Brain research. Molecular brain research
- 1 October 1993
Opioid peptides derived from the precursor, prodynorphin, are co-localized with vasopressin in the hypothalamus and posterior pituitary, and vasopressin and prodynorphin synthesis are coordinately… Expand