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Optimization of curcumin nanoemulsion for intranasal delivery using design of experiment and its toxicity assessment.
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Nose to brain transport pathways an overview: potential of nanostructured lipid carriers in nose to brain targeting
Abstract Many of the therapeutics used for the treatment of brain disorders are not effective and not delivered to the brain due to the complex structure and its barriers. In recent years, many…
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Investigation of preparation parameters of nanosuspension by top-down media milling to improve the dissolution of poorly water-soluble glyburide.
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Optimization of artemether-loaded NLC for intranasal delivery using central composite design
TLDR
ARM-NLC showed highest drug targeting efficiency and drug transport percentage which indicates NLC had better brain targeting efficiency compared to drug solution, which indicates the developed formulations were non-toxic and safe for intranasal administration.
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Olanzapine Loaded Cationic Solid Lipid Nanoparticles for Improved Oral Bioavailability
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Dissolution Testing for Poorly Soluble Drugs: A Continuing Perspective
TLDR
Whatever method is used by the dissolution scientists, it must aim towards the cheaper but most effective approach to enhance the dissolution behavior of poorly soluble drugs.
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Intranasal therapeutic strategies for management of Alzheimer’s disease
TLDR
The aim of this review is to discuss and summarize the latest findings of some of the major studies on IN drug delivery in AD models, with a focus on the potential efficacy of neuroprotective treatments.
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Impact of solid carriers and spray drying on pre/post-compression properties, dissolution rate and bioavailability of solid self-nanoemulsifying drug delivery system loaded with simvastatin
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Development of buccal tablets for curcumin using Anacardium occidentale gum
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Oxaliplatin immuno hybrid nanoparticles for active targeting: an approach for enhanced apoptotic activity and drug delivery to colorectal tumors
TLDR
OIHNPs can effectively deliver the drug to the tumor sites, which can be attributed to its ability in reducing tumor mass and tumor volume in xenograft tumor models in vivo along with sustaining its release in vitro.
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