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Mammalian valyl‐tRNA synthetase forms a complex with the first elongation factor
The high‐molecular‐mass form of valyl‐tRNA synthetase is associated with the first elongation factor activity. It includes two polypeptides of about 50 kDa and two others of 40 and 30 kDa, identifiedExpand
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Purification and properties of a high-molecular-mass complex between Val-tRNA synthetase and the heavy form of elongation factor 1 from mammalian cells.
In extracts of various mammalian tissues obtained in the presence of protease inhibitors Val-tRNA synthetase exists exclusively as a complex with a molecular mass of about 800 kDa. This complex wasExpand
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Crystal structures of native and recombinant yeast fumarase.
Crystal structures for both native and recombinant forms of yeast fumarase from Saccharomyces cerevisiae have been completed to moderate resolution by two separate laboratories. The recombinant formExpand
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Evolution of self-assembly of probionts.
Abstract The process of evolution of organic compounds that led to the emergence of life can be divided into two major stages: chemical and prebiological. Chemical evolution developed at theExpand
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Purification of valyl‐tRNA synthetase high‐molecular‐mass complex from rabbit liver
A high‐molecular‐mass complex containing valyl‐tRNA synthetase has been purified to homogeneity from rabbit liver. The molecular mass of the complex is about 800 kDa. The complex consists of fourExpand
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Anticodon‐dependent aminoacylation of RNA minisubstrate by lysyl‐tRNA synthetase
Specific inhibition of mammalian lysyl‐tRNA synthetase by polyU is shown. Inhibition of the enzyme is dependent on the length of the oligonucleotide, since oligoU molecules with a length of less thanExpand
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Purification, characterization and preliminary X-ray study of fumarase from Saccharomyces cerevisiae.
Fumarase (fumarate hydratase, EC 4.2.1.2) from Saccharomyces cerevisiae has been purified to homogeneity by a method including acetone fractionation, DEAE ion-exchange and dye-sorbent affinityExpand
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DNA content of radiosensitive organs of albino rats exposed to radiation at high altitude and following adaptation to hypoxia in a pressure chamber. [Gamma radiation]
Pre-exposure of rats to hypoxia attenuates the postradiation decrease in DNA content (..mu..g/mg dry tissue or protein) of the spleen, bone marrow and thymus in the destructive period of radiationExpand