Share This Author
Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex
Improved visualization of protein consensus sequences by iceLogo
- Niklaas Colaert, Kenny Helsens, L. Martens, J. Vandekerckhove, K. Gevaert
- BiologyNature Methods
- 1 November 2009
FASP method is described as “universal” for its ability to represent the proteome in an unbiased way, which was demonstrated by comparison to the transcriptome by demonstrating a disproportionate reduction in peptide ion current, peptide or protein identifications.
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
- T. Arnesen, P. Van Damme, K. Gevaert
- BiologyProceedings of the National Academy of Sciences
- 19 May 2009
Although the COmbined FRActional DIagonal Chromatography technology was used to determine the N-terminal acetylation status of 742 human and yeast protein N termini, it was revealed that NatA from humans and yeast have identical or nearly identical specificities.
Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability
Protein N-terminal acetyltransferases: when the start matters.
LNCipedia: a database for annotated human lncRNA transcript sequences and structures
The authors' analyses suggest that, much like microRNAs, many lncRNAs have a significant secondary structure, in-line with their presumed association with proteins or protein complexes, which may serve as a resource to initiate small- and large-scale lncRNA studies.
T‐cell receptor‐induced JNK activation requires proteolytic inactivation of CYLD by MALT1
It is shown that T‐cell receptors (TCR) activation, as well as overexpression of the oncogenic API2–MALT1 fusion protein, results in proteolytic inactivation of CYLD by MALT1, which is specifically required for c‐jun N‐terminal kinase (JNK) activation and the inducible expression of a subset of genes.
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides
A diagonal method to isolate N-terminal peptides from in vivo blocked proteins based on diagonal electrophoresis and diagonal chromatography is described.
LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
ANGUSTIFOLIA3 Binds to SWI/SNF Chromatin Remodeling Complexes to Regulate Transcription during Arabidopsis Leaf Development[W]
The data indicate that AN3 associates with chromatin remodelers to regulate transcription, and place the SWI/SNF-AN3 module as a major player at the transition from cell proliferation to cell differentiation in a developing leaf.