K. G. Young

Publications33
h-index13
Citations601
Highly Influential Citations46
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INF1 is a novel microtubule-associated formin.
Formin proteins, characterized by the presence of conserved formin homology (FH) domains, play important roles in cytoskeletal regulation via their abilities to nucleate actin filament formation and… Expand
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Spectrin repeat proteins in the nucleus
Spectrin repeat sequences are among the more common repeat elements identified in proteins, typically occurring in large structural proteins. Examples of spectrin repeat‐containing proteins include… Expand
  • 58
  • 4
Formins in cell signaling.
The founding formin homology protein family members were implicated early on as being involved in regulating cytoskeletal remodeling pathways, as formin protein mutations in Drosophila and yeast lead… Expand
  • 97
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Dystonin/Bpag1--a link to what?
The dystonin/Bpag1 cytoskeletal interacting proteins play important roles in maintaining cytoarchitecture integrity in skin and in the neuromuscular system. The most profound phenotype observed in… Expand
  • 56
  • 4
Genetic alterations at the Bpag1 locus in dt mice and their impact on transcript expression
The dystonin/Bpag1 gene encodes several tissue-specific alternatively spliced transcripts that encode cytoskeletal binding proteins. These various isoforms are necessary for maintaining the… Expand
  • 37
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Gonadotropin‐releasing hormone neuronal system of the freshwater snails Helisoma trivolvis and Lymnaea stagnalis: Possible involvement in reproduction
Peptides of the gonadotropin‐releasing hormone (GnRH) family are present in neural and nonneural tissues throughout the chordate phylum. Although GnRH peptides have been implicated in nonreproductive… Expand
  • 67
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A Bpag1 isoform involved in cytoskeletal organization surrounding the nucleus.
Bpag1/dystonin proteins are giant cytoskeletal interacting proteins postulated to cross-link cytoskeletal filaments and thereby maintain cellular integrity. Loss of function of non-epithelial Bpag1… Expand
  • 40
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CD8+ T Cells Primed in the Periphery Provide Time-Bound Immune-Surveillance to the Central Nervous System
After vaccination, memory CD8+ T cells migrate to different organs to mediate immune surveillance. In most nonlymphoid organs, following an infection, CD8+ T cells differentiate to become long-lived… Expand
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Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus
Plakins are a family of giant cytoskeleton binding proteins. One member of this group is bullous pemphigoid antigen 1 (Bpag1)/dystonin, which has neuronal and muscle isoforms that consist of… Expand
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Involvement of protein kinase C in 5‐HT‐stimulated ciliary activity in Helisoma trivolvis embryos
1 During development, embryos of the pulmonate gastropod, Helisoma trivolvis, undergo a rotation behaviour due to the co‐ordinated beating of three bands of ciliated epithelial cells. This behaviour… Expand
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